Not Yet RecruitingN/AOther
Hemodynamic Responses to Laryngoscopy and Tracheal Intubation
Sponsored by Assiut University
NCT ID
NCT07783256
Target Enrollment
70 participants
Start Date
2026-12-20
Est. Completion
2028-12-20
About This Study
Laryngoscopy and tracheal intubation lead to tachycardia and hypertension due to increase in the plasma catecholamines subsequent to sympathetic stimulation.
Conditions Studied
Interventions
- •ketodex
- •ketofol
Eligibility
Age:18 Years - 60 Years
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria: * Adult patients scheduled for elective middle ear surgery under general anesthesia, ASA status I-II, aged from 18 to 60 years old of either sex. Exclusion Criteria: * Full stomach or emergency surgery * Any known contraindications or allergy to ketamine, dexmedetomidine, or propofol * Pregnancy or breastfeeding women * Body mass index (BMI) \> 35 Kg/m2 * History of hepatic, renal, or cardiac disease * Patients in whom the duration of laryngoscopy will last more than 25 seconds * Chronic opioid use, or history of neuropsychiatric disorders * Patient refusal