415 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 961–1008 of 1750 trials
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin After Trauma Surgery for Pain
Trent Emerick
Pain ManagementPostoperative Pain
Not Yet Recruiting·Phase 2·psilocybin
Study of Psilocybin Under Anesthesia Controlled by EEG
Stanford University
Major Depression
Not Yet Recruiting·Phase 4·ketamine
Biomarker-Guided Antidepressant Selection
Weill Medical College of Cornell University
Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)rTMS+2 more
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin as a Novel Therapy for Residual Anhedonia
NYU Langone Health
AnhedoniaEmotional Blunting
Not Yet Recruiting·Phase 2·ketamine
Pilot Randomized Control Trial Comparing Oral Ketamine and Oral Oxycodone for Pain Control in Emergency Department Patients
Albany Medical College
Pain Management
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
Brigham and Women's Hospital
Alcohol Use Disorder
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
Yale University
Chronic Low Back Pain (CLBP)Physical TherapyPsilocybin
Not Yet Recruiting·Phase 2·ketamine
Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse
University of Oklahoma
Head and Neck Cancer
Not Yet Recruiting·Phase 2·ketamine
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
University of Rochester
Treatment Resistant Depression (TRD)Chronic Pain
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy as a Treatment for Depression
Washington University School of Medicine
Depression
Not Yet Recruiting·N/A·MDMA
Circulating Oxytocin Changes in Response to MDMA vs. Placebo in Adult Patients With Autism Spectrum Disorder and Matched Healthy Controls
University Hospital, Basel, Switzerland
Autism Spectrum Disorder
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy
Emory University
PTSD
Not Yet Recruiting·Phase 2·psilocybin
Group Retreat Psilocybin Therapy for Healthcare Clinicians With Loss of Meaning in Their Work and Symptoms of Depression
University of Washington
DepressionAnxiety
Not Yet Recruiting·N/A·Other
Multimodal Pharmacological Study of Clinical Cohorts for Major Depressive Disorder
Shanghai Mental Health Center
Major Depressive Disorder (MDD
Not Yet Recruiting·Phase 3·psilocybin
Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder
Lakshmi N Yatham
Bipolar II Depression
Not Yet Recruiting·Phase 1·Other
Opioid-free Anesthesia and Postoperative Delirium
Qianfoshan Hospital
Postoperative DeliriumGastrointestinal Tumors
Not Yet Recruiting·N/A·LSD
Effect of LSD on Renal Function in Cirrhosis Patients With Portal Hypertension Bleeding (2-Year Follow-Up)
Northern Jiangsu People's Hospital
Cirrhosis, LiverSplenectomy; StatusRenal Function Abnormal+1 more
Not Yet Recruiting·Phase 2·psilocybin
Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy
Kyle Greenway
Treatment-Resistant Major Depressive Disorder
Not Yet Recruiting·Phase 3·ketamine
InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression
Sunnybrook Health Sciences Centre
Treatment Resistant Depression
Not Yet Recruiting·N/A·ketamine
A 2×2 Factorial Randomized Controlled Trial for ERCP
Gang Chen
Biliary and Pancreatic DiseasesEndoscopic Retrograde Cholangiopancreatography (ERCP)
Not Yet Recruiting·N/A·ketamine
Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery
Tanta University
ObesityPostoperative PainBariatric Surgery
Not Yet Recruiting·Phase 2·ketamine
KALM-B: Ketamine-assisted Psychotherapy (KAP) to Lessen Morbidity After Burn Injury
Irma Fleming
PTSD and Trauma-related Symptoms
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin AsSisted pSychotherapy for the treatmENt of Gambling disordER : a Pilot Study
Nantes University Hospital
Gambling Disorder
Not Yet Recruiting·Phase 1·DMT
Pharmacokinetics and Safety of GH001 Delivered Via a GH001 Aerosol Delivery System in Healthy Subjects
GH Research Ireland Limited
Healthy Adult
Not Yet Recruiting·Phase 1·MDMA
MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function
Resilient Pharmaceuticals
PharmacokineticsHepatic Impairment
Not Yet Recruiting·N/A·ketamine
Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery
Aga Khan University
Breast CancerPain, ChronicPost Surgical Pain
Not Yet Recruiting·Phase 1·ketamine
KF2025#1 Trial: Ketamine, Cannabidiol and Cobicistat Interaction Study
Helsinki University Central Hospital
Drug Drug Interaction
Not Yet Recruiting·N/A·Other
Comparison Between Two Drugs in Sedation of Upper GI Endoscopy
Zagazig University
Sedation During GI Endoscopy
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder
Centre for Addiction and Mental Health
Major Depressive Disorder (MDD)Alcohol Use Disorder (AUD)
Not Yet Recruiting·Phase 3·Other
Intravenous Lidocaine Plus Port-Site Ropivacaine for Recovery After Laparoscopic Surgery
Centre Hospitalier Universitaire, Amiens
Intravenous LidocaineLaparoscopic SurgeryPost Operative Recovery+1 more
Not Yet Recruiting·Phase 2·ketamine
Sufentanil Versus Ketamine Intranasally in the Management of Severe Acute Trauma-related Pain in Children.
Fondation Lenval
TraumatologyWounds and InjuryFractures Bone+4 more
Not Yet Recruiting·N/A·ketamine
Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery
Nanjing First Hospital, Nanjing Medical University
Post Induction Hypotension
Not Yet Recruiting·N/A·Other
Influence of Therapeutic Failure on the Psychosocial Experience in Multiple Sclerosis
University Hospital, Caen
Multiple Sclerosis
Not Yet Recruiting·N/A·ketamine
Comparison of Nebulized Ketamine With Nebulized Magnesium Sulfate for the Prevention of Postoperative Sore Throat
Sohag University
Postoperative Sore Throat
Not Yet Recruiting·Phase 3·ketamine
Optimal Timing of Ketamine Initiation for SCD Pain
Boston Children's Hospital
Sickle Cell DiseaseSickle Cell Crisis
Not Yet Recruiting·Phase 2·ketamine
Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement
University of California, San Diego
Opioid Use Disorder
Not Yet Recruiting·Phase 3·ketamine
Ketamine Irrigation Analgesia in Laparoscopic Cholecystectomy
Assiut University
Pain
Not Yet Recruiting·Phase 3·ketamine
Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia
Zagazig University
Postoperative AnalgesiaPostoperative Pain Management
Not Yet Recruiting·N/A·ketamine
Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression
Chinese PLA General Hospital
DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·N/A·ketamine
Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression
Chinese PLA General Hospital
DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·Phase 2·psilocybin
Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter
NYU Langone Health
Stuttering
Not Yet Recruiting·Phase 1·Other
Magnesium Sulfate in Pediatric Burn Dressing Changes
Hennepin Healthcare Research Institute
Pediatric Burns
Not Yet Recruiting·Phase 1·ketamine
Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.
Liaquat National Hospital & Medical College
SedationPreoperative Anxiety Experienced by the Pediatric PatientAnxiolytic Effect+1 more
Not Yet Recruiting·N/A·Other
Role of Opioid Free Anaesthesia in Elderly Patients Undergoing Elective Coronary Artery Bypass Graft Surgeries With Cardiopulmonary Bypass in Enhanced Recovery After Surgeries
Ain Shams University
CABGDexmedetomidineKetamine+2 more
Not Yet Recruiting·Phase 1·ketamine
Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain
Kansas City Heart Rhythm Research Foundation
Pain Management
Not Yet Recruiting·Phase 2·ketamine
Safety and Efficacy of Lidocaine Versus Ketamine Infusion for Resistant Orofacial Pain
Assiut University
Orofacial Pain
Not Yet Recruiting·Phase 3·ketamine
Comparison of Intranasal Ketorolac and Intranasal Ketamine in Digital Nerve Block Pain
Tehran University of Medical Sciences
PainDigital Block
Not Yet Recruiting·Phase 1·ketamine
Ketamine Biomarker Validation
Soterix Medical
Treatment Resistant Depression (TRD)
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.