415 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 1009–1056 of 1750 trials
Not Yet Recruiting·N/A·Other
Anesthesia Management in Endovascular Therapy for Ischemic Stroke - 2
University Hospital, Clermont-Ferrand
Ischemic StrokeAnterior Cerebral CirculationGeneral Anesthesia+2 more
Not Yet Recruiting·Phase 4·ketamine
Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT（ESSENCE）
Chinese PLA General Hospital
Postoperative Pain
Not Yet Recruiting·Phase 4·ketamine
Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial
Assiut University
Varicocelectomy
Not Yet Recruiting·Phase 4·ketamine
Ketamine for the Treatment of Refractory Status Epilepticus
Thomas Jefferson University
Refractory Status Epilepticus
Not Yet Recruiting·N/A·Other
Intravenous Sedation and Analgesia Versus Local Anesthesia During Microwave Ablation of Benign Thyroid Nodules
Suez University
Benign Thyroid Nodule
Not Yet Recruiting·Phase 2·psilocybin
Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)
Centre Hospitalier St Anne
Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)
Not Yet Recruiting·N/A·LSD
Microdosing LSD in Women With Premenstrual Disorders
Friederike Holze
PMSPMDD
Not Yet Recruiting·Phase 1·ketamine
Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD
Queen's University
Chronic PainPosttraumatic Stress Disorder (PTSD)
Not Yet Recruiting·Phase 3·ketamine
Ketamine Sedation in the ICU (KANINE) RCT
McMaster University
Mechanical VentilationCritically Ill Intensive Care Unit Patients
Not Yet Recruiting·Phase 3·ketamine
Comparison of Esketamine Nasal Spray vs.Aripiprazole in Treat.Resistant Major Depressive Disorder in Elderly Patients
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Depressive Disorder
Not Yet Recruiting·Phase 4·Other
Opioid-Free Versus Opioid-Based Anesthesia in Bariatric
Siirt Training and Research Hospital
ObesityBariatric Surgery
Not Yet Recruiting·N/A·ketamine
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
IVO JURISIC
Obese PatientsBariatric Surgical PainBariatric Surgery (Sleeve Gastrectomy )+6 more
Not Yet Recruiting·Phase 3·Other
A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis
Asklepion Pharmaceuticals, LLC
Sickle Cell Disease
Not Yet Recruiting·N/A·ketamine
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Zagazig University
Emergence Delirium, Anesthesia
Not Yet Recruiting·N/A·ketamine
Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children
Anqing Municipal Hospital
EtomidateEsketamineTonsillectomy+1 more
Not Yet Recruiting·N/A·Other
Effectiveness of the Combination Strategy of Disease-Modifying Therapy and the Yishen Daluo Yin Modified Formula for Multiple Sclerosis
Ying Gao
RRMS
Not Yet Recruiting·Phase 4·ketamine
Ketamine for Postherpetic Neuralgia With Depression
Huazhong University of Science and Technology
Depression DisordersHerpetic Neuralgia
Not Yet Recruiting·Early Phase 1·ketamine
Ketamine and Lidocaine Infusion in Refractory Chronic Migraine
Assiut University
Refractory Chronic Migraine
Not Yet Recruiting·N/A·Other
Cladribine Tablets as an Exit Therapy Strategy
University Hospital, Strasbourg, France
Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
Not Yet Recruiting·Phase 3·ketamine
Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents
Federal University of São Paulo
Depressive DisorderSuicidal Ideas
Not Yet Recruiting·Early Phase 1·ketamine
Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients
University of Zurich
Depressive Symptoms Mild to Moderate in SeverityAnxietyQuality of Life (QOL)+2 more
Not Yet Recruiting·N/A·Other
Opioid-free Anesthesia and Quality of Recovery After General Anesthesia
Selcuk University
Opioid-free AnesthesiaGeriatric Population
Not Yet Recruiting·Phase 4·ketamine
Feasibility of Closed-loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine
bo xu
General Anesthesia With PropofolClosed-Loop
Not Yet Recruiting·Phase 4·Other
Comparative Study of Opioid-Free Anesthesia Versus Opioid Anesthesia in Patients Undergoing Laparoscopic Cholecystectomy
Assiut University
Laparoscopic Cholecystectomy
Not Yet Recruiting·Phase 3·DMT
Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)
University Hospital, Strasbourg, France
Relapsing-remitting Multiple Sclerosis (RRMS)
Not Yet Recruiting·Phase 2·Other
PEX010-Assisted Therapy for Stimulant Use Disorder: A Safety, Feasibility and Efficacy Study
Filament Health Corp.
Stimulant Use Disorder
Not Yet Recruiting·N/A·Other
Acupressure's Impact on Pain and Physiological Parameters in Infants Undergoing Cardiac Catheterization
Baskent University
Cardiac Catheterization
Not Yet Recruiting·N/A·ketamine
Opioid Free Anesthesia Versus Opioid Based Anesthesia
Ain Shams University
Opioid Free AnesthesiaLaparoscopic Bariatric Surgeries
Not Yet Recruiting·Phase 1·Other
Axitinib and Oral Metronomic Etoposide for Pediatric Children and AYA Refractory/Relapsing Medulloblastoma and Ependymoma
Assistance Publique Hopitaux De Marseille
MedulloblastomaEpendymoma
Not Yet Recruiting·Phase 2·ketamine
Quelling of Excitotoxicity in Acute Stroke With Ketamine
Lower Merion Neurology Research Foundation
Acute Ischemic Stroke
Not Yet Recruiting·Phase 2·ketamine
Ketamine Treatment for PTSD and MDD in TBI
Minneapolis Veterans Affairs Medical Center
PTSD, Post Traumatic Stress DisorderMajor Depressive DisorderTraumatic Brain Injury
Recruiting·Early Phase 1·psilocybin
Psilocybin Administration With 5-HT1a Blockade
Johns Hopkins University
Psychedelic Effects in Healthy Volunteers
Recruiting·Phase 3·ketamine
A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression
Janssen Research & Development, LLC
Depressive Disorder, Treatment-Resistant
Recruiting·Phase 2·ketamine
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
Joshua Rosenblat
Borderline Personality Disorder (BPD)Treatment-Resistant Major Depressive DisorderTreatment-resistant Bipolar Depression+4 more
Recruiting·Phase 1·Other
Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA
Neutrolis
SLE (Systemic Lupus)RA - Rheumatoid Arthritis
Recruiting·Early Phase 1·psilocybin
Psilocybin as a Treatment for Chronic Pain in Smokers
Yale University
Smokers With Chronic Pain
Recruiting·Phase 2·psilocybin
Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression
Centre for Addiction and Mental Health
Treatment-Resistant Depression
Recruiting·Early Phase 1·MDMA
MDMA-assisted Therapy for Fibromyalgia
Spaulding Rehabilitation Hospital
Fibromyalgia
Recruiting·Phase 2·psilocybin
Mindfulness-based Psilocybin Therapy for PTSD
Anthony P King
Post Traumatic Stress DisorderDepression - Major Depressive Disorder
Recruiting·Phase 2·psilocybin
The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease
Yale University
DepressionParkinson's Disease (PD)
Recruiting·Phase 1·psilocybin
Psilocybin Efficacy With or Without Pimavanserin Pretreatment
Johns Hopkins University
Mood (Psychological Function)Well BeingMood+1 more
Recruiting·Phase 2·MDMA
MDMA-Assisted Massed Exposure Therapy for PTSD
Emory University
Post Traumatic Stress Disorder
Recruiting·Phase 3·psilocybin
Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms
Centre Hospitalier Universitaire de Nīmes
Alcohol Use DisorderDepressive SympotomsPsilocybin
Recruiting·Phase 2·MDMA
MDMA Therapy in Veterans With PTSD
Sunstone Medical
Post Traumatic Stress Disorder
Recruiting·N/A·Other
Comparison of Two General Anesthesia Maintenance Strategies on Intraoperative Visibility During Arthroscopic Rotator Cuff Surgery: A Randomized Trial
Centre Hospitalier Universitaire de Nice
Rotator Cuff InjuriesAnesthesia, GeneralArthroscopy
Recruiting·Phase 3·Other
A Prospective Randomized Non-inferiority Trial Comparing Anti-CD20 Maintenance Versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis
University Hospital, Montpellier
Relapsing-Remitting Multiple Sclerosis (RRMS)Anti-CD20 Therapy
Recruiting·Early Phase 1·ketamine
Ketamine in Severe Traumatic Brain Injury
University of Texas Southwestern Medical Center
Traumatic Brain InjuryTraumatic Encephalopathy
Recruiting·Phase 1·psilocybin
A Study of Psychedelics in Healthy Older Adults With Low Well-being
Jennifer Mitchell
Anhedonia in Healthy VolunteersOlder Adults (50-90 Years)
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.