411 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 1057–1104 of 1767 trials
Recruiting·N/A·Other
Quality of Recovery-15 After Opioid-free Versus Opioid-based General Anesthesia in Major Urological Surgery
Jagiellonian University
Postoperative RecoveryAnesthesia, GeneralAnalgesics, Opioid+1 more
Recruiting·Phase 2·psilocybin
Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
NYU Langone Health
Alcohol Use Disorder
Recruiting·Phase 1·psilocybin
Psilocybin as a Novel Therapy for Residual Anhedonia
NYU Langone Health
AnhedoniaEmotional Blunting
Recruiting·Phase 2·psilocybin
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
COMPASS Pathways
PTSD - Post Traumatic Stress DisorderPTSDPTSD Symptoms+1 more
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for Intergenerational Trauma
Rachel Yehuda
Psychological StressDepressionAnxiety
Recruiting·Phase 2·ketamine
KALM-B: Ketamine-assisted Psychotherapy (KAP) to Lessen Morbidity After Burn Injury
Irma Fleming
PTSD and Trauma-related Symptoms
Recruiting·Early Phase 1·psilocybin
Psilocybin Administration With 5-HT1a Blockade
Johns Hopkins University
Psychedelic Effects in Healthy Volunteers
Recruiting·Phase 4·ketamine
Biomarker-Guided Antidepressant Selection
Weill Medical College of Cornell University
Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)rTMS+2 more
Recruiting·Phase 1·psilocybin
Psilocybin to Treat Depression in Spinal Cord Injury
James J. Peters Veterans Affairs Medical Center
Spinal Cord InjuryDepression - Major Depressive DisorderVeteran
Recruiting·Phase 3·psilocybin
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
VA Office of Research and Development
Major Depression
Recruiting·Phase 3·ketamine
A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression
Janssen Research & Development, LLC
Depressive Disorder, Treatment-Resistant
Recruiting·Phase 2·psilocybin
Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa
Region Skane
Anorexia Nervosa
Recruiting·Phase 2·ketamine
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
Joshua Rosenblat
Borderline Personality Disorder (BPD)Treatment-Resistant Major Depressive DisorderTreatment-resistant Bipolar Depression+4 more
Recruiting·N/A·Other
Prospective Multicentre Observational Registry of Peri-procedural Anaesthesia, Sedation and Related Medication Exposure in Patients With Brugada Syndrome
Hospital Clinic of Barcelona
Brugada Syndrome (BrS)Ventricular ArrhythmiaAnesthesia+1 more
Recruiting·Phase 1·Other
Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA
Neutrolis
SLE (Systemic Lupus)RA - Rheumatoid Arthritis
Recruiting·Early Phase 1·psilocybin
Psilocybin as a Treatment for Chronic Pain in Smokers
Yale University
Smokers With Chronic Pain
Recruiting·Phase 2·psilocybin
Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression
Centre for Addiction and Mental Health
Treatment-Resistant Depression
Recruiting·Phase 2·psilocybin
Mindfulness-based Psilocybin Therapy for PTSD
Anthony P King
Post Traumatic Stress DisorderDepression - Major Depressive Disorder
Recruiting·Phase 2·MDMA
MDMA-Assisted Massed Exposure Therapy for PTSD
Emory University
Post Traumatic Stress Disorder
Recruiting·Phase 2·psilocybin
The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease
Yale University
DepressionParkinson's Disease (PD)
Recruiting·Phase 2·MDMA
MDMA Therapy in Veterans With PTSD
Sunstone Medical
Post Traumatic Stress Disorder
Recruiting·Phase 3·psilocybin
Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms
Centre Hospitalier Universitaire de Nīmes
Alcohol Use DisorderDepressive SympotomsPsilocybin
Recruiting·Phase 2·psilocybin
Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)
Centre Hospitalier St Anne
Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)
Recruiting·N/A·Other
Comparison of Two General Anesthesia Maintenance Strategies on Intraoperative Visibility During Arthroscopic Rotator Cuff Surgery: A Randomized Trial
Centre Hospitalier Universitaire de Nice
Rotator Cuff InjuriesAnesthesia, GeneralArthroscopy
Recruiting·Phase 3·Other
A Prospective Randomized Non-inferiority Trial Comparing Anti-CD20 Maintenance Versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis
University Hospital, Montpellier
Relapsing-Remitting Multiple Sclerosis (RRMS)Anti-CD20 Therapy
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder
Lakshmi N Yatham
Bipolar II Depression
Recruiting·Phase 1·psilocybin
A Study of Psychedelics in Healthy Older Adults With Low Well-being
Jennifer Mitchell
Anhedonia in Healthy VolunteersOlder Adults (50-90 Years)
Recruiting·Early Phase 1·ketamine
Ketamine in Severe Traumatic Brain Injury
University of Texas Southwestern Medical Center
Traumatic Brain InjuryTraumatic Encephalopathy
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD
Unity Health Toronto
Post Traumatic Stress DisorderPTSDChronic PTSD
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD
Sunstone Medical
Post Traumatic Stress DisorderPTSD
Recruiting·Phase 1·MDMA
MDMA Assisted Therapy for BN
Icahn School of Medicine at Mount Sinai
Bulimia Nervosa
Recruiting·Phase 2·MDMA
MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder
VA Office of Research and Development
Post Traumatic Stress DisorderAlcohol Use Disorder
Recruiting·Phase 1·psilocybin
Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.
Francisco A Moreno
Obsessive-Compulsive Disorder
Recruiting·Phase 2·psilocybin
Subjective Experience Following Psilocybin
University of Calgary
Investigating the Importance of the Subjective Psychedelic Experience
Recruiting·Phase 2·ketamine
Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients
Hospital Italiano de Buenos Aires
Critical IllnessDepressive Symptoms
Recruiting·Phase 3·Other
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
Definium Therapeutics US, Inc.
Major Depressive Disorder
Recruiting·Phase 3·ketamine
InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression
Sunnybrook Health Sciences Centre
Treatment Resistant Depression
Recruiting·N/A·Other
Multimodal Anesthesia in Robotic Laparoscopic Nephrectomy
Fundacio Puigvert
AnesthesiaAnesthesia and Procedure Related Time IntervalsNephrectomy / Methods
Recruiting·Phase 1·psilocybin
Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder
University of New Mexico
PTSD
Recruiting·N/A·Other
An International Federated Model for Wearable-derived Remote Longitudinal Motor Monitoring in Young Children With Spinal Muscular Atrophy Compared With Healthy Controls: Active-NBS Study (UK)
University of Oxford
Spinal Muscular Atrophy (SMA)
Recruiting·N/A·Other
Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients
Zeliha Alicikus
Critically IllIntubation ComplicationOxygenation+3 more
Recruiting·N/A·ketamine
Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression
Massachusetts General Hospital
Treatment Resistant Depression (TRD)
Recruiting·Early Phase 1·ketamine
Ketamine and Propofol NeuroImaging
Keith M Vogt
AnesthesiaPain
Recruiting·N/A·Other
A Study Comparing Effectiveness of Kesimpta® (Ofatumumab) Versus Ocrevus® (Ocrelizumab) in Real-world Practice
Novartis Pharmaceuticals
Multiple Sclerosis
Recruiting·Phase 1·psilocybin
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
Healthy VolunteerOlder Adults (65-85 Years)
Recruiting·Phase 1·psilocybin
Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer
Gustavo Vazquez
DemoralizationSafety
Recruiting·Early Phase 1·ketamine
Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine
University of Pennsylvania
Major Depressive Disorder (MDD)
Recruiting·Phase 1·ketamine
Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD
Dr. Yuliya Knyahnytska
Chronic PainPosttraumatic Stress Disorder (PTSD)
Browse by Condition
View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.