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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 12491296 of 1750 trials
Recruiting·Phase 4·ketamine

The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury

Rigshospitalet, Denmark

Subarachnoid Hemorrhage, AneurysmalIntracerebral HemorrhageTraumatic Brain Injury
Recruiting·Phase 1·ketamine

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

Yale University

Depressive Disorder, MajorPost Traumatic Stress Disorder
Recruiting·Phase 2·ketamine

Enhancing Week-long Psychological Treatment for PTSD With Ketamine

Yale University

Posttraumatic Stress Disorder
Recruiting·N/A·Other

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

Oregon Health and Science University

Obstructive Sleep ApneaDown Syndrome
Recruiting·Phase 2·psilocybin

Psilocybin Therapy in Advanced Cancer

NYU Langone Health

Advanced Cancer
Recruiting·Phase 3·ketamine

Oral Ketamine for Treatment of Vaso-Occlusive Pain

Boston Children's Hospital

Vaso-occlusive Crisis
Recruiting·N/A·Other

Different Treatments in Chronic Pain Patients.

University Ghent

Chronic PainNociplastic Pain
Recruiting·Phase 2·ketamine

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

Yale University

Depressive DisorderMajor Depressive DisorderBipolar Disorder+2 more
Recruiting·N/A·ketamine

Metabolic Profiling of Esketamine Treatment in Depressive Disorder

University of Zagreb

Major Depressive Disorder
Recruiting·N/A·ketamine

IV Ketamine vs. IN Esketamine for MDD TRD

Gustavo Vazquez

Treatment Resistant Depression
Recruiting·N/A·ketamine

Study of the Neural Circuits Underlying the Negative Emotional Bias of Depressive Disorders and Their Response to Ketamine

Centre Hospitalier St Anne

Depressive Disorder
Recruiting·Phase 2·ketamine

Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

The University of Texas Health Science Center at San Antonio

Suicide
Recruiting·N/A·ketamine

Ketamine Treatment Plans for Chronic Conditions

RIVER Foundation

Chronic PainDepressive DisorderAnxiety Disorders+1 more
Recruiting·N/A·Other

Opioid-free Anaesthesia in Breast Cancer Surgery

University of Ioannina

Breast CancerAnesthesiaPain, Postoperative+3 more
Recruiting·Phase 2·Other

Improving Neurotrauma by Depolarization Inhibition With Combination Therapy (INDICT)

University of Cincinnati

Traumatic Brain Injury
Recruiting·Early Phase 1·ketamine

Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine

Emory University

Major Depressive Disorder
Recruiting·Phase 4·ketamine

Comparison of Esketamine/Propofol and Methohexital Anesthesia for ECT

Medical University of Vienna

ECTDepression
Recruiting·N/A·ketamine

Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression

Riccardo Guglielmo

Depression and Quality of LifeTreatment Resistant Depression (TRD)Anhedonia+5 more
Recruiting·Early Phase 1·ketamine

Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

Cedars-Sinai Medical Center

AnxietyPancreatic Cancer
Recruiting·Phase 1·ketamine

Glutamatergic Mechanisms: Aim2

New York State Psychiatric Institute

Healthy
Recruiting·Phase 4·ketamine

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

Massachusetts General Hospital

Major Depressive Disorder
Recruiting·Phase 2·MDMA

MDMA-assisted Therapy for Adjustment Disorder (AD) in Dyads of Patients With Cancer and a Concerned Significant Other

Sunstone Medical

CancerAdjustment Disorders
Recruiting·Phase 2·Other

Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea

Erin Kirkham

Obstructive Sleep Apnea
Recruiting·N/A·ketamine

Ketamine in OCD: Efficacy and Effects on Stress and Cognition

Medical University of Vienna

Obsessive-Compulsive DisorderPsychiatric Disorder
Recruiting·Phase 2·ketamine

The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy

Madeline Fields

Drug Resistant EpilepsyMedically Refractory EpilepsyRefractory Epilepsy
Recruiting·Phase 3·ketamine

Ketamine Treatment of Youth Suicide Attempters

Tatiana Falcone, MD

Suicide, Attempted
Recruiting·Phase 3·ketamine

Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches

University Health Network, Toronto

Chronic Daily Headache
Recruiting·Phase 4·ketamine

Ketamine as a Supplement to Local Anesthesia for Minor Procedures

Loyola University

Pain, ProceduralMinor LacerationAbscess
Recruiting·Phase 1·psilocybin

Effects of Psilocybin on Electrophysiology and the Dynamic Content of Thought

Johns Hopkins University

Healthy
Recruiting·Phase 1·ketamine

Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer

Natalie Lockney

Head and Neck CancerLocally Advanced Head and Neck Carcinoma
Recruiting·Phase 4·Other

Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC

University of Crete

Systemic Inflammatory Response SyndromePostoperative Pain, AcutePostoperative Pain, Chronic+4 more
Recruiting·Phase 4·ketamine

Ketamine in Acute Brain Injury Patients.

Geert Meyfroidt, MD, PhD

Brain Injuries, Traumatic
Recruiting·N/A·ketamine

Long-term Observation of Participants With Mood Disorders

National Institute of Mental Health (NIMH)

DepressionSuicide Risk
Recruiting·Phase 1·ketamine

Understanding Ketamine's Dissociative Effects (KD Study)

Stanford University

Epilepsy
Recruiting·Phase 1·ketamine

Ketamine Assisted Psychotherapy for Opioid Use Disorder

University of Utah

Opioid-use Disorder
Recruiting·Early Phase 1·psilocybin

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

Johns Hopkins University

Depressive SymptomsDepressionAlzheimer Disease+1 more
Recruiting·Phase 1·psilocybin

Adjunctive Effects of Psilocybin and a Formulation of Buprenorphine

University of Wisconsin, Madison

Opioid Use Disorder
Recruiting·Phase 2·ketamine

Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI

Sam Tyagi

Descending Aortic DissectionPostoperative PainThoracoabdominal Aortic Aneurysm
Recruiting·N/A·ketamine

University of Iowa Interventional Psychiatry Service Patient Registry

Mark Niciu

Treatment Resistant DepressionMajor Depressive EpisodeMajor Depression+4 more
Recruiting·Phase 4·Other

Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair

University of Crete

Elective Surgical ProceduresPostoperative PainAnesthesia+5 more
Recruiting·Phase 4·ketamine

Ketamine for Post-operative Analgesia in Hemorrhoidectomy

University of Oklahoma

Hemorrhoids
Recruiting·Phase 2·ketamine

Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation

Naveen Poonai

FractureDislocation
Recruiting·Phase 1·ketamine

Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression

National Institute of Mental Health (NIMH)

DepressionMajor Depressive DisorderMajor Depression
Recruiting·Phase 3·DMT

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

National Institute of Allergy and Infectious Diseases (NIAID)

Relapsing Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
Recruiting·N/A·ketamine

Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery

Göteborg University

ObesityPain, Postoperative
Recruiting·Phase 4·ketamine

Premedication for Less Invasive Surfactant Administration

University of Oulu

Surfactant Deficiency Syndrome Neonatal
Recruiting·Phase 2·LSD

Lysergic Acid Diethylamide (LSD) as Treatment for Cluster Headache

University Hospital, Basel, Switzerland

Cluster Headache
Recruiting·N/A·ketamine

Anesthetics and Analgesics in Children

Chi Dang Hornik

AnesthesiaPain
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.