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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 529576 of 1031 trials
Completed·Phase 1·ketamine

Nicotinic Modulation of Schizophrenia-like Information Processing Deficits in Healthy Subjects

Yale University

Healthy Subjects
Completed·N/A·ketamine

Ondansetron Reduce Vomiting Associated With Ketamine PSA

University of Colorado, Denver

Conscious Sedation
Completed·Phase 4·ketamine

Preoperative Ketamine Has no Preemptive Analgesic Effect in Patients Undergoing Colon Surgery.

Hospital Arquitecto Marcide

Pain, Postoperative
Completed·N/A·ketamine

Ketamine/Placebo Family History Positive Study

Yale University

Alcoholism
Completed·Phase 2·ketamine

Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain

Javelin Pharmaceuticals

Pain, Postoperative
Enrolling by Invitation·Phase 4·ketamine

The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.

University of Missouri-Columbia

Spine Surgery
Enrolling by Invitation·N/A·ketamine

Psychotherapy Combined With Intranasal Esketamine for the Treatment of Suicidal Ideation

University of California, San Diego

Suicidal Ideation
Enrolling by Invitation·Phase 2·ketamine

Ketamine Effects on Learning In Eating Disorders

Amanda Downey, MD

Anorexia NervosaAtypical Anorexia Nervosa
Enrolling by Invitation·N/A·ketamine

Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions

Psyrin Inc.

Obsessive Compulsive Disorder (OCD)Bipolar DisordersMajor Depressive Disorder+2 more
Enrolling by Invitation·N/A·ketamine

Cognitive Training as an Adjunct to Ketamine in Real-world Clinics

University of Pittsburgh

Depression
Enrolling by Invitation·N/A·ketamine

Long Term Follow Up KET-PD

Yale University

Parkinson's DiseaseDepression
Enrolling by Invitation·Phase 4·ketamine

Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan

Brigham and Women's Hospital

Acute Suicidal Depression (ASD)
Enrolling by Invitation·N/A·ketamine

Prediction of REsponse to Depression Interventions Using Clinical and TD-fNIRS Measurements

Kernel

DepressionMajor Depressive Disorder
Enrolling by Invitation·N/A·ketamine

Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)

Medical University of Gdansk

Major Depressive DisorderPost Traumatic Stress DisorderObsessive-Compulsive Disorder+3 more
Enrolling by Invitation·N/A·ketamine

Observational Study of Ketamine Infusions for the Treatment of Chronic Pain

Theresa Lii

Chronic Pain
Enrolling by Invitation·N/A·ketamine

Long-term Pain Modulation by Intravenous Esketamine in CRPS

Erasmus Medical Center

Complex Regional Pain SyndromesCRPS (Complex Regional Pain Syndromes)
Enrolling by Invitation·N/A·ketamine

Effect of Ketamine and Etomidate During RSI on Long Term Outcomes

Vanderbilt University Medical Center

Post-Traumatic Stress DisorderAcute Respiratory Failure
Enrolling by Invitation·Phase 4·ketamine

Ketamine Infusion for Neuropathic Pain in Brachial Plexus Injuries

Mayo Clinic

Brachial Plexus Injury
Enrolling by Invitation·N/A·ketamine

Safety and Efficacy of Ketamine Intravenous Infusions in the Treatment of Fibromyalgia

Wilderman Medical Clinic

Fibromyalgia
Not Yet Recruiting·Phase 2·ketamine

Adjunctive Oral KET-AD Capsules in Treatment Resistant Bipolar Depression

Neurocentrx Pharma Pty Ltd

Treatment Resistant Bipolar Depression
Not Yet Recruiting·Phase 3·ketamine

KetAmine and Recovery After Mechanical VentilAtion ( KARMA )

Assistance Publique - Hôpitaux de Paris

Critical Illness
Not Yet Recruiting·Phase 1·ketamine

Oral and Sublingual Ketamine

Western University, Canada

Major Depression Severe
Not Yet Recruiting·Phase 4·ketamine

Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal Thoughts

New York State Psychiatric Institute

Major Depressive Disorder (MDD)
Not Yet Recruiting·Phase 3·ketamine

Morphine or Ketamine for Analgesia

Columbia University

Abdominal PainIsolated Extremity FracturePain+1 more
Not Yet Recruiting·Phase 2·ketamine

Nebulized Ketamine Plus Standard Care vs. Standard Care Alone in Moderate to Severe Asthma Exacerbations

Oman Medical Speciality Board

Asthma AcuteAsthma AttackAsthma Exacerbations
Not Yet Recruiting·Phase 2·ketamine

Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder

University Hospital, Toulouse

Infusion of Ketamine in Severe Borderline Personality DisorderBorderline Personality Disorder (BPD)
Not Yet Recruiting·N/A·ketamine

Testing Two Doses of Nebulized Ketamine for Postoperative Sore Throat

Aswan University Hospital

Postoperative Sore Throat
Not Yet Recruiting·Phase 2·ketamine

Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers

National Center for Complementary and Integrative Health (NCCIH)

Healthy Volunteers
Not Yet Recruiting·Phase 4·ketamine

Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis

University of Mississippi Medical Center

Vaso-Occlusive Pain Episode in Sickle Cell DiseaseSickle Cell Disease (SCD)
Not Yet Recruiting·N/A·ketamine

Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.

China-Japan Friendship Hospital

Knee OsteoarthritisReplacement, KneeElective Surgical Patients+1 more
Not Yet Recruiting·Phase 4·ketamine

Intraperitoneal Ketamine Versus Fentanyl as Adjuvants to Bupivacaine in Laparoscopic Cholecystectomy

Assiut University

Postoperative Pain
Not Yet Recruiting·N/A·ketamine

Outcomes Registry After Ketamine Infusions for Chronic Pain: A Longitudinal Evaluation

Stanford University

Chronic PainKetamine
Not Yet Recruiting·N/A·ketamine

Intra-Sessional Autonomic Arc Detection in Ketamine-Assisted Therapy for PTSD: A Signal Characterisation Pilot Study

Adriaan Dirk van der Wart

Post-Traumatic Stress Disorder
Not Yet Recruiting·N/A·ketamine

Esketamine Versus Sufentanil for Sedation in Patients Undergoing ERCP

Ren Da

Biliary Tract DiseasesProcedural Sedation and Analgesia
Not Yet Recruiting·Phase 4·ketamine

Biomarker-Guided Antidepressant Selection

Weill Medical College of Cornell University

Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)rTMS+2 more
Not Yet Recruiting·Phase 2·ketamine

Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study

University of Michigan

HealthyCovert Consciousness
Not Yet Recruiting·Phase 2·ketamine

Pilot Randomized Control Trial Comparing Oral Ketamine and Oral Oxycodone for Pain Control in Emergency Department Patients

Albany Medical College

Pain Management
Not Yet Recruiting·Phase 2·ketamine

Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression

University of Rochester

Treatment Resistant Depression (TRD)Chronic Pain
Not Yet Recruiting·Phase 2·ketamine

Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse

University of Oklahoma

Head and Neck Cancer
Not Yet Recruiting·Phase 3·ketamine

InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression

Sunnybrook Health Sciences Centre

Treatment Resistant Depression
Not Yet Recruiting·N/A·ketamine

A 2×2 Factorial Randomized Controlled Trial for ERCP

Gang Chen

Biliary and Pancreatic DiseasesEndoscopic Retrograde Cholangiopancreatography (ERCP)
Not Yet Recruiting·N/A·ketamine

Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery

Tanta University

ObesityPostoperative PainBariatric Surgery
Not Yet Recruiting·Phase 2·ketamine

KALM-B: Ketamine-assisted Psychotherapy (KAP) to Lessen Morbidity After Burn Injury

Irma Fleming

PTSD and Trauma-related Symptoms
Not Yet Recruiting·N/A·ketamine

Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery

Aga Khan University

Breast CancerPain, ChronicPost Surgical Pain
Not Yet Recruiting·Phase 1·ketamine

KF2025#1 Trial: Ketamine, Cannabidiol and Cobicistat Interaction Study

Helsinki University Central Hospital

Drug Drug Interaction
Not Yet Recruiting·Phase 2·ketamine

Sufentanil Versus Ketamine Intranasally in the Management of Severe Acute Trauma-related Pain in Children.

Fondation Lenval

TraumatologyWounds and InjuryFractures Bone+4 more
Not Yet Recruiting·N/A·ketamine

Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery

Nanjing First Hospital, Nanjing Medical University

Post Induction Hypotension
Not Yet Recruiting·N/A·ketamine

Comparison of Nebulized Ketamine With Nebulized Magnesium Sulfate for the Prevention of Postoperative Sore Throat

Sohag University

Postoperative Sore Throat
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.