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Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 577–624 of 1031 trials
Not Yet Recruiting·Phase 3·ketamine
Optimal Timing of Ketamine Initiation for SCD Pain
Boston Children's Hospital
Sickle Cell DiseaseSickle Cell Crisis
Not Yet Recruiting·Phase 2·ketamine
Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement
University of California, San Diego
Opioid Use Disorder
Not Yet Recruiting·Phase 3·ketamine
Ketamine Irrigation Analgesia in Laparoscopic Cholecystectomy
Assiut University
Pain
Not Yet Recruiting·Phase 3·ketamine
Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia
Zagazig University
Postoperative AnalgesiaPostoperative Pain Management
Not Yet Recruiting·N/A·ketamine
Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression
Chinese PLA General Hospital
DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·N/A·ketamine
Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression
Chinese PLA General Hospital
DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·Phase 1·ketamine
Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.
Liaquat National Hospital & Medical College
SedationPreoperative Anxiety Experienced by the Pediatric PatientAnxiolytic Effect+1 more
Not Yet Recruiting·Phase 2·ketamine
Safety and Efficacy of Lidocaine Versus Ketamine Infusion for Resistant Orofacial Pain
Assiut University
Orofacial Pain
Not Yet Recruiting·Phase 1·ketamine
Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain
Kansas City Heart Rhythm Research Foundation
Pain Management
Not Yet Recruiting·Phase 3·ketamine
Comparison of Intranasal Ketorolac and Intranasal Ketamine in Digital Nerve Block Pain
Tehran University of Medical Sciences
PainDigital Block
Not Yet Recruiting·Phase 1·ketamine
Ketamine Biomarker Validation
Soterix Medical
Treatment Resistant Depression (TRD)
Not Yet Recruiting·Phase 4·ketamine
Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT（ESSENCE）
Chinese PLA General Hospital
Postoperative Pain
Not Yet Recruiting·Phase 4·ketamine
Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial
Assiut University
Varicocelectomy
Not Yet Recruiting·Phase 4·ketamine
Ketamine for the Treatment of Refractory Status Epilepticus
Thomas Jefferson University
Refractory Status Epilepticus
Not Yet Recruiting·Phase 3·ketamine
Ketamine Sedation in the ICU (KANINE) RCT
McMaster University
Mechanical VentilationCritically Ill Intensive Care Unit Patients
Not Yet Recruiting·Phase 1·ketamine
Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD
Queen's University
Chronic PainPosttraumatic Stress Disorder (PTSD)
Not Yet Recruiting·Phase 3·ketamine
Comparison of Esketamine Nasal Spray vs.Aripiprazole in Treat.Resistant Major Depressive Disorder in Elderly Patients
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Depressive Disorder
Not Yet Recruiting·N/A·ketamine
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
IVO JURISIC
Obese PatientsBariatric Surgical PainBariatric Surgery (Sleeve Gastrectomy )+6 more
Not Yet Recruiting·N/A·ketamine
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Zagazig University
Emergence Delirium, Anesthesia
Not Yet Recruiting·N/A·ketamine
Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children
Anqing Municipal Hospital
EtomidateEsketamineTonsillectomy+1 more
Not Yet Recruiting·Phase 4·ketamine
Ketamine for Postherpetic Neuralgia With Depression
Huazhong University of Science and Technology
Depression DisordersHerpetic Neuralgia
Not Yet Recruiting·Early Phase 1·ketamine
Ketamine and Lidocaine Infusion in Refractory Chronic Migraine
Assiut University
Refractory Chronic Migraine
Not Yet Recruiting·Phase 3·ketamine
Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents
Federal University of São Paulo
Depressive DisorderSuicidal Ideas
Not Yet Recruiting·Early Phase 1·ketamine
Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients
University of Zurich
Depressive Symptoms Mild to Moderate in SeverityAnxietyQuality of Life (QOL)+2 more
Not Yet Recruiting·Phase 4·ketamine
Feasibility of Closed-loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine
bo xu
General Anesthesia With PropofolClosed-Loop
Not Yet Recruiting·N/A·ketamine
Opioid Free Anesthesia Versus Opioid Based Anesthesia
Ain Shams University
Opioid Free AnesthesiaLaparoscopic Bariatric Surgeries
Not Yet Recruiting·Phase 2·ketamine
Quelling of Excitotoxicity in Acute Stroke With Ketamine
Lower Merion Neurology Research Foundation
Acute Ischemic Stroke
Not Yet Recruiting·Phase 2·ketamine
Ketamine Treatment for PTSD and MDD in TBI
Minneapolis Veterans Affairs Medical Center
PTSD, Post Traumatic Stress DisorderMajor Depressive DisorderTraumatic Brain Injury
Recruiting·Phase 3·ketamine
A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression
Janssen Research & Development, LLC
Depressive Disorder, Treatment-Resistant
Recruiting·Phase 2·ketamine
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
Joshua Rosenblat
Borderline Personality Disorder (BPD)Treatment-Resistant Major Depressive DisorderTreatment-resistant Bipolar Depression+4 more
Recruiting·Early Phase 1·ketamine
Ketamine in Severe Traumatic Brain Injury
University of Texas Southwestern Medical Center
Traumatic Brain InjuryTraumatic Encephalopathy
Recruiting·Phase 2·ketamine
Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients
Hospital Italiano de Buenos Aires
Depression DisorderKetamine
Recruiting·N/A·ketamine
Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression
Massachusetts General Hospital
Treatment Resistant Depression (TRD)
Recruiting·Early Phase 1·ketamine
Ketamine and Propofol NeuroImaging
Keith M Vogt
AnesthesiaPain
Recruiting·Early Phase 1·ketamine
Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine
University of Pennsylvania
Major Depressive Disorder (MDD)
Recruiting·Phase 2·ketamine
Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults
Mohsen Saidinejad
Sickle Cell DiseaseVaso-Occlusive Pain Episode in Sickle Cell DiseaseKetamine Infusion+2 more
Recruiting·N/A·ketamine
ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1
Salma Health, Inc.
Depressed Mood
Recruiting·Phase 3·ketamine
Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)
University of Virginia
Status Epilepticus
Recruiting·Phase 1·ketamine
Prospective IR-led Sedation Feasibility
CAMC Health System
AnesthesiaSedation and AnalgesiaInterventional Radiology
Recruiting·Phase 2·ketamine
Ketamine for Veterans With Parkinson's Disease
VA Office of Research and Development
Parkinson's Disease
Recruiting·Early Phase 1·ketamine
The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain.
National and Kapodistrian University of Athens
Opioid-Refractory Chronic Cancer-Related Pain
Recruiting·Phase 2·ketamine
Ketamine for Opioid Use Disorder
University of Maryland, Baltimore
Opioid Use Disorder
Recruiting·Phase 1·ketamine
Pilot Study of RR-HNK in OCD
Carolyn Rodriguez
Obsessive-Compulsive Disorder
Recruiting·Phase 2·ketamine
Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.
The Ketamine Research Foundation
Phantom Limb Syndrome With Pain
Recruiting·Phase 3·ketamine
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder
Janssen Research & Development, LLC
Depressive Disorder, Major
Recruiting·Phase 2·ketamine
Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression
VA Office of Research and Development
Chronic Low Back PainDepression
Recruiting·Phase 2·ketamine
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
ACADIA Pharmaceuticals Inc.
Major Depressive Disorder (MDD)Depressive Disorder, Treatment-Resistant
Recruiting·Phase 4·ketamine
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
Texas Tech University Health Sciences Center
Orthopedic Trauma Surgery PatientsPostoperative PainOpioid Use+2 more
Browse by Condition
View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.