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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 625672 of 1031 trials
Recruiting·N/A·ketamine

Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant Depression

Hospital Universitari Vall d'Hebron Research Institute

Depression - Major Depressive DisorderDepression DisorderDepression Chronic+1 more
Recruiting·N/A·ketamine

Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension

University General Hospital of Patras

Magnesium SulfateRemifentanilS 100beta+6 more
Recruiting·N/A·ketamine

Analgosedation With Ketamine, Nalbuphine, or Dexmedetomidine for Suture Removal in Children After Cleft Surgery

University Medical Centre Ljubljana

Orofacial CleftsCleft Lip and PalateAlveolar Ridge Defect
Recruiting·Phase 3·ketamine

Pain Control Alternatives in Pediatric Patients With Distal Radius Fractures

State University of New York at Buffalo

Distal Radius Fracture ReductionPain ControlPediatric Fractures
Recruiting·Phase 4·ketamine

Magnesium and Cramping

Corewell Health East

Uterine CrampsPostoperative Pain ManagementHysteroscopy
Recruiting·Phase 1·ketamine

A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression

Juliana Zambrano, MD, MPH

Depression
Recruiting·Phase 3·ketamine

Ketamine Augmentation of ECT in Treatment-Resistant Depression

Università Vita-Salute San Raffaele

Major Depressive DisorderTreatment Resistant Depression
Recruiting·Phase 2·ketamine

A Study of Ketamine Infusions to Treat Clinically-depressed ICU Patients

Mayo Clinic

Depression
Recruiting·Phase 2·ketamine

Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD

Northwestern University

Posttraumatic HeadachePosttraumatic Stress Disorder
Recruiting·N/A·ketamine

Music as an Adjunct to Ketamine Therapy for Chronic Pain

McGill University

Chronic PainChronic Noncancer Pain
Recruiting·N/A·ketamine

Working Mechanisms and Effectiveness of IV Ketamine-assisted Psychotherapy on Depression in TRD Clients

Senz

Treatment Resistant Depression
Recruiting·Phase 2·ketamine

Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder

Dr. med. Marcus Herdener

Alcohol Abuse/DependenceAlcohol Use Disorder (AUD)Alcoholism
Recruiting·N/A·ketamine

Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments

Neuronetics

DepressionOCDAnxiety Depression
Recruiting·N/A·ketamine

ACT_for Alcohol Use Disorder and Depression

Centre hospitalier de l'Université de Montréal (CHUM)

Depression - Major Depressive DisorderAlcohol Use Disorder
Recruiting·Phase 3·ketamine

Best Hypnotic Drug Choice for Rapid Sequence Induction in the Operating Room

Nantes University Hospital

Rapid Sequence Induction
Recruiting·Phase 2·ketamine

Understanding and Treating Suicidal Ideation With Ketamine

The Royal's Institute of Mental Health Research

Suicidal IdeationMajor Depressive Disorder (MDD)
Recruiting·Phase 3·ketamine

Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine

Assistance Publique - Hôpitaux de Paris

Limb Injury
Recruiting·Phase 2·ketamine

Intravenous Ketamine for Treatment-Resistant Depression

Mayo Clinic

Depressive Disorder, Treatment-ResistantTreatment Resistant Depression (TRD)
Recruiting·Phase 3·ketamine

PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study

Yale University

Depression
Recruiting·Phase 1·ketamine

Ketamine for Combined Depression and Alcohol Use Disorder

University Hospital of North Norway

DepressionAlcohol Use Disorder
Recruiting·Phase 2·ketamine

Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression

Icahn School of Medicine at Mount Sinai

Major Depressive Disorder
Recruiting·Phase 2·ketamine

Ketamine Sedation As Neuroprotective Agent Following Out-of-hospital Cardiac Arrest

Christian Hassager

Out-of-hospital Cardiac Arrest (OHCA)
Recruiting·Phase 4·ketamine

Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose Ketamine

Insel Gruppe AG, University Hospital Bern

Endometriosis
Recruiting·N/A·ketamine

Veteran's Perceptions of Ketamine-Assisted Psychotherapy for Depression and End-of-Life

Albany Research Institute, Inc.

Depression
Recruiting·Phase 2·ketamine

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

National Institute of Mental Health (NIMH)

SuicideDepressive Disorder, Treatment-ResistantKetamine+10 more
Recruiting·Phase 3·ketamine

Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients

Assistance Publique - Hôpitaux de Paris

Major Depressive Episode
Recruiting·Phase 3·ketamine

Nebulized Ketamine for the Treatment of Major Depressive Disorder

Theresa Jacob, PhD, MPH

Severe DepressionModerate DepressionKetamine+14 more
Recruiting·Phase 4·ketamine

The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD

Margaux M. Salas, PhD

Neuropathic PainPTSD
Recruiting·Phase 1·ketamine

(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain

Rush University Medical Center

Pain, Neuropathic
Recruiting·Phase 2·ketamine

Imaging Depression in Parkinson's Disease

Yale University

Parkinson's DiseaseMajor Depressive Disorder
Recruiting·Phase 3·ketamine

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.

Dr. Inge Winter

Major Depressive DisorderTreatment Resistant Depression
Recruiting·Phase 4·ketamine

Low-Dose Ketamine Infusion During Burn Wound Care

University of Tennessee

BurnPainDissociation+1 more
Recruiting·N/A·ketamine

Effect of Opioid-Free vs Opioid-Based Anesthesia on Postoperative Pain and Emergence Agitation in Children Undergoing Cleft Surgery

Iva Smiljanić

Cleft Lip PalateOrofacial CleftAgitation, Emergence+3 more
Recruiting·N/A·ketamine

Belief Updating in Treatment Resistant Depression

Assistance Publique - Hôpitaux de Paris

Treatment Resistant Depression
Recruiting·Phase 1·ketamine

Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

Lindsay Maguire, MD

SuicideSuicidal IdeationDepression
Recruiting·Phase 4·ketamine

Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED

Antonios Likourezos

Pain, Acute
Recruiting·Phase 2·ketamine

Pharmacologic Treatment Augmentation in Chronic Depression

University Hospital Tuebingen

Major Depressive Disorder
Recruiting·Phase 3·ketamine

Esketamine as Treatment for Chronic Pain Due to Endometriosis: a RCT Study

Reinier de Graaf Groep

EndometriosisChronic Pelvic Pain Syndrome
Recruiting·Phase 2·ketamine

Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)

Stanford University

Obsessive-Compulsive Disorder
Recruiting·Phase 2·ketamine

Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction

Dr. med. Marcus Herdener

Cocaine Use DisorderCocaine Dependence
Recruiting·Phase 4·ketamine

Neural Circuit Effects of Ketamine in Depression

Icahn School of Medicine at Mount Sinai

Major Depressive Disorder
Recruiting·N/A·ketamine

The OBSERVE Protocol

Yale University

Major Depression Disorder
Recruiting·Phase 3·ketamine

Fentanyl or Esketamine for Traumatic PAIN (FORE-PAIN) Trial

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Acute Pain Due to TraumaAnalgesiaFentanyl+2 more
Recruiting·Phase 2·ketamine

i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial

University Health Network, Toronto

Major Depressive DisorderSuicideTreatment Resistant Depression
Recruiting·Phase 1·ketamine

Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression

Texas A&M University

HealthyMajor Depressive DisorderTreatment Resistant Depression
Recruiting·Phase 3·ketamine

Effect of Ketamine on Intraoperative Motor Evoked Potentials

University of California, San Francisco

Spine FusionSpine TumorSpinal Stenosis
Recruiting·Phase 3·ketamine

Prehospital Analgesia INtervention Trial (PAIN)

Jason Sperry

Traumatic Injury
Recruiting·Phase 1·ketamine

HNC: Human Neural Circuits Electrophysiology During Cognition

Stanford University

Psychiatric Disorder
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.