180 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 673720 of 1031 trials
Recruiting·N/A·ketamine

RIVER At Home Ketamine Protocols

RIVER Foundation

Chronic ConditionChronic PainChronic Disease+3 more
Recruiting·Phase 4·ketamine

The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury

Rigshospitalet, Denmark

Subarachnoid Hemorrhage, AneurysmalIntracerebral HemorrhageTraumatic Brain Injury
Recruiting·Phase 1·ketamine

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

Yale University

Depressive Disorder, MajorPost Traumatic Stress Disorder
Recruiting·Phase 2·ketamine

Enhancing Week-long Psychological Treatment for PTSD With Ketamine

Yale University

Posttraumatic Stress Disorder
Recruiting·Phase 3·ketamine

Oral Ketamine for Treatment of Vaso-Occlusive Pain

Boston Children's Hospital

Vaso-occlusive Crisis
Recruiting·Phase 2·ketamine

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

Yale University

Depressive DisorderMajor Depressive DisorderBipolar Disorder+2 more
Recruiting·N/A·ketamine

Metabolic Profiling of Esketamine Treatment in Depressive Disorder

University of Zagreb

Major Depressive Disorder
Recruiting·N/A·ketamine

IV Ketamine vs. IN Esketamine for MDD TRD

Gustavo Vazquez

Treatment Resistant Depression
Recruiting·N/A·ketamine

Study of the Neural Circuits Underlying the Negative Emotional Bias of Depressive Disorders and Their Response to Ketamine

Centre Hospitalier St Anne

Depressive Disorder
Recruiting·Phase 2·ketamine

Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

The University of Texas Health Science Center at San Antonio

Suicide
Recruiting·N/A·ketamine

Ketamine Treatment Plans for Chronic Conditions

RIVER Foundation

Chronic PainDepressive DisorderAnxiety Disorders+1 more
Recruiting·Early Phase 1·ketamine

Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine

Emory University

Major Depressive Disorder
Recruiting·Phase 4·ketamine

Comparison of Esketamine/Propofol and Methohexital Anesthesia for ECT

Medical University of Vienna

ECTDepression
Recruiting·N/A·ketamine

Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression

Riccardo Guglielmo

Depression and Quality of LifeTreatment Resistant Depression (TRD)Anhedonia+5 more
Recruiting·Early Phase 1·ketamine

Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

Cedars-Sinai Medical Center

AnxietyPancreatic Cancer
Recruiting·Phase 1·ketamine

Glutamatergic Mechanisms: Aim2

New York State Psychiatric Institute

Healthy
Recruiting·Phase 4·ketamine

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

Massachusetts General Hospital

Major Depressive Disorder
Recruiting·N/A·ketamine

Ketamine in OCD: Efficacy and Effects on Stress and Cognition

Medical University of Vienna

Obsessive-Compulsive DisorderPsychiatric Disorder
Recruiting·Phase 2·ketamine

The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy

Madeline Fields

Drug Resistant EpilepsyMedically Refractory EpilepsyRefractory Epilepsy
Recruiting·Phase 3·ketamine

Ketamine Treatment of Youth Suicide Attempters

Tatiana Falcone, MD

Suicide, Attempted
Recruiting·Phase 3·ketamine

Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches

University Health Network, Toronto

Chronic Daily Headache
Recruiting·Phase 4·ketamine

Ketamine as a Supplement to Local Anesthesia for Minor Procedures

Loyola University

Pain, ProceduralMinor LacerationAbscess
Recruiting·Phase 1·ketamine

Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer

Natalie Lockney

Head and Neck CancerLocally Advanced Head and Neck Carcinoma
Recruiting·Phase 4·ketamine

Ketamine in Acute Brain Injury Patients.

Geert Meyfroidt, MD, PhD

Brain Injuries, Traumatic
Recruiting·N/A·ketamine

Long-term Observation of Participants With Mood Disorders

National Institute of Mental Health (NIMH)

DepressionSuicide Risk
Recruiting·Phase 1·ketamine

Understanding Ketamine's Dissociative Effects (KD Study)

Stanford University

Epilepsy
Recruiting·Phase 1·ketamine

Ketamine Assisted Psychotherapy for Opioid Use Disorder

University of Utah

Opioid-use Disorder
Recruiting·Phase 2·ketamine

Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI

Sam Tyagi

Descending Aortic DissectionPostoperative PainThoracoabdominal Aortic Aneurysm
Recruiting·N/A·ketamine

University of Iowa Interventional Psychiatry Service Patient Registry

Mark Niciu

Treatment Resistant DepressionMajor Depressive EpisodeMajor Depression+4 more
Recruiting·Phase 4·ketamine

Ketamine for Post-operative Analgesia in Hemorrhoidectomy

University of Oklahoma

Hemorrhoids
Recruiting·Phase 2·ketamine

Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation

Naveen Poonai

FractureDislocation
Recruiting·Phase 1·ketamine

Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression

National Institute of Mental Health (NIMH)

DepressionMajor Depressive DisorderMajor Depression
Recruiting·N/A·ketamine

Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery

Göteborg University

ObesityPain, Postoperative
Recruiting·Phase 4·ketamine

Premedication for Less Invasive Surfactant Administration

University of Oulu

Surfactant Deficiency Syndrome Neonatal
Recruiting·N/A·ketamine

Anesthetics and Analgesics in Children

Chi Dang Hornik

AnesthesiaPain
Recruiting·N/A·ketamine

Ketamine Enhances Analgesia and Mood in Chronic Pain Patients

Salem Anaesthesia Pain Clinic

Mood Disorder; OpioidMood Insomnia
Recruiting·N/A·ketamine

Dexmedetomidine and Ketamine in VATS Surgery

Ciusss de L'Est de l'Île de Montréal

Postoperative PainOpioid Use
Recruiting·Phase 4·ketamine

ECT with Ketamine Anesthesia Vs High Intensity Ketamine with ECT Rescue for Treatment-Resistant Depression

University of Saskatchewan

Treatment Resistant DepressionKetamine
Recruiting·Phase 1·ketamine

Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

National Institute of Mental Health (NIMH)

Healthy VolunteerMajor Depressive DisorderDepression
Recruiting·Phase 2·ketamine

Neurobiology of Suicide

National Institute of Mental Health (NIMH)

Healthy VolunteersDepression
Recruiting·Phase 2·ketamine

Ketamine Alcohol (in Treatment-Resistant Depression)

Mark Niciu

Magnetic Resonance ImagingMajor DepressionAlcoholism
Suspended·Phase 2·ketamine

Ketamine HCl Prolonged Release Oral Tablets for CRPS

University of Southern California

Complex Regional Pain Syndromes
Suspended·Early Phase 1·ketamine

Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)

University of Wisconsin, Madison

Posttraumatic Stress Disorder
Suspended·Phase 1·ketamine

Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery

University of Utah

PainPostpartum Depression
Suspended·Phase 4·ketamine

Ketamine for Sedation in Severe Traumatic Brain Injury

Henry M. Jackson Foundation for the Advancement of Military Medicine

Severe Traumatic Brain InjuryIntracranial HypertensionIntracranial Hemorrhage, Hypertensive
Suspended·N/A·ketamine

Testing the Effectiveness of Cognitive Training Among Depressed Patients Receiving Esketamine Treatment

University of Pittsburgh

Depression
Suspended·Phase 2·ketamine

Randomized, Double-Blind, Active Placebo-Controlled Study of Ketamine to Treat Levodopa-Induced Dyskinesia

PharmaTher Inc.

DyskinesiasMovement DisordersCentral Nervous System Diseases+2 more
Suspended·Phase 4·ketamine

IM Ketamine vs Midazolam for Suicidal ER Patients

New York State Psychiatric Institute

Depression, UnipolarDepression, BipolarSuicidal Ideation
PreviousPage 15 of 22Next

Browse by Condition

View all conditions →

How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.