347 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 97–144 of 347 trials
Not Yet Recruiting·Phase 3·ketamine

Optimal Timing of Ketamine Initiation for SCD Pain

Boston Children's Hospital

Sickle Cell DiseaseSickle Cell Crisis
Not Yet Recruiting·Phase 3·ketamine

Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia

Zagazig University

Postoperative AnalgesiaPostoperative Pain Management
Not Yet Recruiting·N/A·ketamine

Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression

Chinese PLA General Hospital

DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·N/A·ketamine

Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression

Chinese PLA General Hospital

DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·Phase 2·psilocybin

Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter

NYU Langone Health

Stuttering
Not Yet Recruiting·Phase 1·ketamine

Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.

Liaquat National Hospital & Medical College

SedationPreoperative Anxiety Experienced by the Pediatric PatientAnxiolytic Effect+1 more
Not Yet Recruiting·Phase 1·ketamine

Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain

Kansas City Heart Rhythm Research Foundation

Pain Management
Not Yet Recruiting·Phase 2·ketamine

Safety and Efficacy of Lidocaine Versus Ketamine Infusion for Resistant Orofacial Pain

Assiut University

Orofacial Pain
Not Yet Recruiting·Phase 3·ketamine

Comparison of Intranasal Ketorolac and Intranasal Ketamine in Digital Nerve Block Pain

Tehran University of Medical Sciences

PainDigital Block
Not Yet Recruiting·Phase 4·ketamine

Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT(ESSENCE)

Chinese PLA General Hospital

Postoperative Pain
Not Yet Recruiting·Phase 4·ketamine

Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial

Assiut University

Varicocelectomy
Not Yet Recruiting·Phase 4·ketamine

Ketamine for the Treatment of Refractory Status Epilepticus

Thomas Jefferson University

Refractory Status Epilepticus
Not Yet Recruiting·N/A·LSD

Microdosing LSD in Women With Premenstrual Disorders

Friederike Holze

PMSPMDD
Not Yet Recruiting·Phase 3·ketamine

Comparison of Esketamine Nasal Spray vs.Aripiprazole in Treat.Resistant Major Depressive Disorder in Elderly Patients

Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Depressive Disorder
Not Yet Recruiting·N/A·ketamine

Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy

IVO JURISIC

Obese PatientsBariatric Surgical PainBariatric Surgery (Sleeve Gastrectomy )+6 more
Not Yet Recruiting·N/A·ketamine

Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children

Anqing Municipal Hospital

EtomidateEsketamineTonsillectomy+1 more
Not Yet Recruiting·Phase 4·ketamine

Ketamine for Postherpetic Neuralgia With Depression

Huazhong University of Science and Technology

Depression DisordersHerpetic Neuralgia
Not Yet Recruiting·Early Phase 1·ketamine

Ketamine and Lidocaine Infusion in Refractory Chronic Migraine

Assiut University

Refractory Chronic Migraine
Not Yet Recruiting·Phase 3·ketamine

Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents

Federal University of São Paulo

Depressive DisorderSuicidal Ideas
Not Yet Recruiting·Early Phase 1·ketamine

Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients

University of Zurich

Depressive Symptoms Mild to Moderate in SeverityAnxietyQuality of Life (QOL)+2 more
Not Yet Recruiting·Phase 4·ketamine

Feasibility of Closed-loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine

bo xu

General Anesthesia With PropofolClosed-Loop
Not Yet Recruiting·Phase 3·DMT

Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)

University Hospital, Strasbourg, France

Relapsing-remitting Multiple Sclerosis (RRMS)
Not Yet Recruiting·Phase 2·ketamine

Quelling of Excitotoxicity in Acute Stroke With Ketamine

Lower Merion Neurology Research Foundation

Acute Ischemic Stroke
Not Yet Recruiting·Phase 2·ketamine

Ketamine Treatment for PTSD and MDD in TBI

Minneapolis Veterans Affairs Medical Center

PTSD, Post Traumatic Stress DisorderMajor Depressive DisorderTraumatic Brain Injury
Recruiting·Phase 2·psilocybin

Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin

National Institute on Aging (NIA)

Alzheimer's Disease
Recruiting·Phase 1·psilocybin

Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility Study

Oregon Health and Science University

Chronic Pelvic Pain
Recruiting·Phase 1·psilocybin

Pilot Study on the Effects of Psilocybin on Belief Updating and Insight Formation

Brown University

Phase I
Recruiting·Phase 1·psilocybin

Psilocybin for Amblyopia - Targeting Critical Periods in Humans

Johns Hopkins University

Amblyopia
Recruiting·Phase 1·psilocybin

Psilocybin Efficacy With or Without Pimavanserin Pretreatment

Johns Hopkins University

Mood (Psychological Function)Well BeingMood+1 more
Recruiting·Phase 3·ketamine

Morphine or Ketamine for Analgesia

Columbia University

Abdominal PainIsolated Extremity FracturePain+1 more
Recruiting·Phase 2·psilocybin

Psilocybin AsSisted pSychotherapy for the treatmENt of Gambling disordER : a Pilot Study

Nantes University Hospital

Gambling Disorder
Recruiting·N/A·DMT

REAL-MS: Observational Database Study of AHSCT and MS Therapies

Imperial College London

Multiple SclerosisMultiple Sclerosis (MS) - Relapsing-remittingMultiple Sclerosis (MS) Primary Progressive
Recruiting·Phase 2·ketamine

Alleviating Suicidality by Combining Psychotherapy and IM Ketamine for Rapid Treatment in the Emergency Department

The University of Texas Health Science Center at San Antonio

Suicidal Ideation
Recruiting·Early Phase 1·MDMA

MDMA-assisted Therapy for Fibromyalgia

Spaulding Rehabilitation Hospital

Fibromyalgia
Recruiting·Phase 2·psilocybin

Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

COMPASS Pathways

PTSD - Post Traumatic Stress DisorderPTSDPTSD Symptoms+1 more
Recruiting·Phase 2·ketamine

Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults

Mohsen Saidinejad

Sickle Cell DiseaseVaso-Occlusive Pain Episode in Sickle Cell DiseaseKetamine Infusion+2 more
Recruiting·Phase 2·psilocybin

Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD

NYU Langone Health

Alcohol Use Disorder
Recruiting·Phase 2·psilocybin

Mindfulness-based Psilocybin Therapy for PTSD

Anthony P King

Post Traumatic Stress DisorderDepression - Major Depressive Disorder
Recruiting·Phase 1·psilocybin

Psilocybin as a Novel Therapy for Residual Anhedonia

NYU Langone Health

AnhedoniaEmotional Blunting
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Intergenerational Trauma

Rachel Yehuda

Psychological StressDepressionAnxiety
Recruiting·Phase 2·ketamine

KALM-B: Ketamine-assisted Psychotherapy (KAP) to Lessen Morbidity After Burn Injury

Irma Fleming

PTSD and Trauma-related Symptoms
Recruiting·Phase 1·DMT

Acute Effects of Intravenous 5-MeO-DMT in Healthy Participants

University Hospital, Basel, Switzerland

5-methoxy-dimethyltryptamine (5-MeO-DMT)
Recruiting·Early Phase 1·psilocybin

Psilocybin Administration With 5-HT1a Blockade

Johns Hopkins University

Psychedelic Effects in Healthy Volunteers
Recruiting·Phase 4·ketamine

Biomarker-Guided Antidepressant Selection

Weill Medical College of Cornell University

Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)rTMS+2 more
Recruiting·Phase 1·psilocybin

Psilocybin to Treat Depression in Spinal Cord Injury

James J. Peters Veterans Affairs Medical Center

Spinal Cord InjuryDepression - Major Depressive DisorderVeteran
Recruiting·Phase 3·psilocybin

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

VA Office of Research and Development

Major Depression
Recruiting·Phase 3·ketamine

A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression

Janssen Research & Development, LLC

Depressive Disorder, Treatment-Resistant
Recruiting·Phase 2·psilocybin

Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa

Region Skane

Anorexia Nervosa
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.