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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 97144 of 284 trials
Completed·Phase 1·psilocybin

Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.

Yale University

Obsessive-Compulsive Disorder
Completed·Phase 1·psilocybin

Psilocybin-assisted Group Therapy for Demoralization in Long-term AIDS Survivors

Joshua Woolley

DistressDepressionGrief
Completed·Phase 1·psilocybin

Psilocybin for the Treatment of Migraine Headache

Yale University

Migraine Headache
Completed·Phase 2·psilocybin

Effects of Psilocybin in Major Depressive Disorder

Johns Hopkins University

Major Depressive Disorder
Completed·Phase 1·psilocybin

Persisting Effects of Psilocybin

Johns Hopkins University

Healthy
Completed·Phase 1·psilocybin

Psilocybin for the Treatment of Cluster Headache

Yale University

Cluster Headache
Completed·Phase 2·psilocybin

Psilocybin-facilitated Treatment for Cocaine Use

University of Alabama at Birmingham

Cocaine-Related Disorders
Completed·Phase 1·psilocybin

The Effects of Psilocybin-Facilitated Experience on the Psychology and Effectiveness of Religious Professionals

NYU Langone Health

Religious or Spiritual Problem
Completed·Phase 1·psilocybin

Effects of Psilocybin-facilitated Experience on the Psychology and Effectiveness of Professional Leaders in Religion

Johns Hopkins University

Healthy
Completed·Phase 1·psilocybin

UW Psilocybin Pharmacokinetics Study

University of Wisconsin, Madison

Healthy
Completed·Phase 2·psilocybin

A Double-Blind Trial of Psilocybin-Assisted Treatment of Alcohol Dependence

NYU Langone Health

Alcohol Dependence
Completed·Phase 1·psilocybin

Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators

Johns Hopkins University

Healthy
Completed·N/A·psilocybin

Beyond the Self and Back: Neuropharmacological Mechanisms Underlying the Dissolution of the Self

University of Zurich

Healthy
Completed·Phase 1·psilocybin

Pilot Study: Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators

Johns Hopkins University

PsilocybinHallucinogensPharmacologic Actions+3 more
Completed·Phase 2·psilocybin

Effects and Therapeutic Potential of Psilocybin in Alcohol Dependence

University of New Mexico

Alcohol Dependence
Completed·Phase 1·psilocybin

Psilocybin and Spiritual Practice

Johns Hopkins University

Healthy
Completed·Early Phase 1·psilocybin

Psilocybin Cancer Anxiety Study

NYU Langone Health

Cancer
Completed·N/A·psilocybin

Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study

Johns Hopkins University

Nicotine Dependence
Completed·Phase 2·psilocybin

Psychopharmacology of Psilocybin in Cancer Patients

Johns Hopkins University

Depressive SymptomsAnxietyCancer
Completed·Phase 1·psilocybin

Effects of Psilocybin in Advanced-Stage Cancer Patients With Anxiety

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Anxiety
Enrolling by Invitation·N/A·psilocybin

Psilocybin-Assisted Group Integration Psychotherapy for Treatment-Resistant Depression

Joshua Rosenblat

Treatment-resistant Depression (TRD)
Enrolling by Invitation·N/A·psilocybin

Salivary Oxytocin as a Biomarker of Psychedelic Treatment

University of Geneva, Switzerland

Major Depressive Disorder (MDD)
Enrolling by Invitation·Phase 3·psilocybin

Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)

Cybin IRL Limited

Major Depressive Disorder
Enrolling by Invitation·Phase 1·psilocybin

Psilocybin With Intracranial Neural Sensing

Joshua Woolley, MD, PhD

Chronic Pain
Enrolling by Invitation·N/A·psilocybin

The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training

Felix Mueller

Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin After Trauma Surgery for Pain

Trent Emerick

Pain ManagementPostoperative Pain
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin for Methamphetamine Use Disorder

Peter Hendricks

Methamphetamine Use Disorder
Not Yet Recruiting·Phase 2·psilocybin

Group PACBT for Depression

University of California, Los Angeles

Depression - Major Depressive DisorderPsilocybinCognitive Behavioral Therapy
Not Yet Recruiting·Phase 1·psilocybin

MLS101 Study in PMDD

MycoMedica Life Sciences PBC

Premenstrual Dysphoric Disorder ( PMDD)PMDD
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life

Charles Raison

AgingLongevityBiomarkers of Aging
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy for Veterans With PTSD

ARQ National Psychotrauma Centre

Posttraumatic Stress Disorder (PTSD)
Not Yet Recruiting·Phase 2·psilocybin

NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy

M.D. Anderson Cancer Center

PsilocybinNeuropathy
Not Yet Recruiting·Phase 1·psilocybin

Pilot Study on the Effects of Psilocybin on Belief Updating and Insight Formation

Brown University

Phase I
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin Therapy for Methamphetamine Use Disorder and HIV

Nicky Mehtani, MD, MPH

Methamphetamine Use DisorderHuman Immunodeficiency Virus (HIV)
Not Yet Recruiting·Phase 2·psilocybin

MB-PAT for Demoralization in Advanced Cancer ('PAT-MIND') Trial

University of Calgary

Advanced CancerDemoralizationExistential Distress+1 more
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility Study

Oregon Health and Science University

Chronic Pelvic Pain
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence

University of Calgary

Post Traumatic Stress Disorder PTSDIntimate Partner Violence (IPV)
Not Yet Recruiting·Phase 2·psilocybin

Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin

National Institute on Aging (NIA)

Alzheimer's Disease
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain

Yale University

Chronic Low Back Pain (CLBP)Physical TherapyPsilocybin
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids

Roswell Park Cancer Institute

Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer: A Randomized Controlled Trial

University Health Network, Toronto

Advanced CancerStage IV Solid Tumor CancerStage IV Sarcoma of Bone+3 more
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin for Treatment of OCD-2

Francisco A Moreno

Obsessive - Compulsive Disorder
Not Yet Recruiting·Phase 1·psilocybin

The Effects of Psilocybin in Healthy Volunteers: Psychological, Biochemical and Electrophysiological Biomarkers.

Gabriella Gobbi

Healthy ParticipantsPlacebo - ControlPsilocybin
Not Yet Recruiting·Phase 1·psilocybin

The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function

Manoj Doss

Healthy
Not Yet Recruiting·Phase 1·psilocybin

Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study

University of Wisconsin, Madison

Well-Being, PsychologicalPsychedelic Experiences
Not Yet Recruiting·Phase 1·psilocybin

The Effects of Psilocybin on Social Connectedness

Yale University

LonelinessGrief
Not Yet Recruiting·Phase 2·psilocybin

Assessing of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies

University of New Mexico

PTSDPTSD - Post Traumatic Stress DisorderMajor Depression+1 more
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder

Brigham and Women's Hospital

Alcohol Use Disorder
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.