347 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 145–192 of 347 trials
Recruiting·Phase 2·ketamine

Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)

Joshua Rosenblat

Borderline Personality Disorder (BPD)Treatment-Resistant Major Depressive DisorderTreatment-resistant Bipolar Depression+4 more
Recruiting·Phase 2·psilocybin

The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease

Yale University

DepressionParkinson's Disease (PD)
Recruiting·Early Phase 1·psilocybin

Psilocybin as a Treatment for Chronic Pain in Smokers

Yale University

Smokers With Chronic Pain
Recruiting·Phase 2·psilocybin

Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression

Centre for Addiction and Mental Health

Treatment-Resistant Depression
Recruiting·Phase 2·ketamine

Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement

University of California, San Diego

Opioid Use Disorder
Recruiting·Phase 2·MDMA

MDMA-Assisted Massed Exposure Therapy for PTSD

Emory University

Post Traumatic Stress Disorder
Recruiting·Phase 2·psilocybin

Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)

Centre Hospitalier St Anne

Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)
Recruiting·Phase 2·MDMA

MDMA Therapy in Veterans With PTSD

Sunstone Medical

Post Traumatic Stress Disorder
Recruiting·Phase 3·psilocybin

Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms

Centre Hospitalier Universitaire de Nīmes

Alcohol Use DisorderDepressive SympotomsPsilocybin
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder

Lakshmi N Yatham

Bipolar II Depression
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy

Emory University

PTSD
Recruiting·Phase 1·psilocybin

A Study of Psychedelics in Healthy Older Adults With Low Well-being

Jennifer Mitchell

Anhedonia in Healthy VolunteersOlder Adults (50-90 Years)
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD

Sunstone Medical

Post Traumatic Stress DisorderPTSD
Recruiting·Phase 1·MDMA

MDMA Assisted Therapy for BN

Icahn School of Medicine at Mount Sinai

Bulimia Nervosa
Recruiting·Phase 1·psilocybin

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

Francisco A Moreno

Obsessive-Compulsive Disorder
Recruiting·Phase 2·MDMA

MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

VA Office of Research and Development

Post Traumatic Stress DisorderAlcohol Use Disorder
Recruiting·Phase 2·psilocybin

Subjective Experience Following Psilocybin

University of Calgary

Investigating the Importance of the Subjective Psychedelic Experience
Recruiting·Phase 2·ketamine

Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients

Hospital Italiano de Buenos Aires

Critical IllnessDepressive Symptoms
Recruiting·Phase 3·ketamine

InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression

Sunnybrook Health Sciences Centre

Treatment Resistant Depression
Recruiting·Phase 1·psilocybin

Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder

University of New Mexico

PTSD
Recruiting·N/A·ketamine

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

Massachusetts General Hospital

Treatment Resistant Depression (TRD)
Recruiting·Early Phase 1·ketamine

Ketamine and Propofol NeuroImaging

Keith M Vogt

AnesthesiaPain
Recruiting·Phase 1·psilocybin

Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer

Gustavo Vazquez

DemoralizationSafety
Recruiting·Phase 1·psilocybin

Safety and Tolerability Trial of Psilocybin in Healthy Older Adults

University of Colorado, Denver

Healthy VolunteerOlder Adults (65-85 Years)
Recruiting·Early Phase 1·ketamine

Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine

University of Pennsylvania

Major Depressive Disorder (MDD)
Recruiting·Phase 1·ketamine

Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD

Dr. Yuliya Knyahnytska

Chronic PainPosttraumatic Stress Disorder (PTSD)
Recruiting·N/A·ketamine

ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1

Salma Health, Inc.

Depressed Mood
Recruiting·Early Phase 1·psilocybin

Psilocybin for Prolonged Grief Disorder

University of Virginia

Prolonged Grief Disorder
Recruiting·Phase 2·psilocybin

Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder

Centre for Addiction and Mental Health

Major Depressive Disorder (MDD)Alcohol Use Disorder (AUD)
Recruiting·Phase 1·MDMA

Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants

University Hospital, Basel, Switzerland

Healhty
Recruiting·Phase 3·ketamine

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

University of Virginia

Status Epilepticus
Recruiting·N/A·LSD

Pharmacokinetics of Didehydro-LSD (DDH-LSD) Compared With LSD

University Hospital, Basel, Switzerland

LSD Reaction
Recruiting·Phase 1·ketamine

Prospective IR-led Sedation Feasibility

CAMC Health System

AnesthesiaSedation and AnalgesiaInterventional Radiology
Recruiting·Early Phase 1·ketamine

The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain.

National and Kapodistrian University of Athens

Opioid-Refractory Chronic Cancer-Related Pain
Recruiting·Phase 2·ketamine

Ketamine for Veterans With Parkinson's Disease

VA Office of Research and Development

Parkinson's Disease
Recruiting·Phase 1·MDMA

MDMA-Assisted Therapy for Mental Healthcare Providers

Rachel Yehuda

Mental Wellbeing
Recruiting·Phase 1·psilocybin

Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

Johns Hopkins University

StrokeChronic StrokeIntracerebral Haemorrhage+9 more
Recruiting·Phase 2·ketamine

Ketamine for Opioid Use Disorder

University of Maryland, Baltimore

Opioid Use Disorder
Recruiting·Phase 3·psilocybin

Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)

Bruyère Health Research Institute.

Psychological Distress
Recruiting·Phase 2·LSD

LSD Treatment for Persons With Alcohol Use Disorder

Felix Mueller

Alcohol Use Disorder (AUD)
Recruiting·Phase 1·ketamine

Pilot Study of RR-HNK in OCD

Carolyn Rodriguez

Obsessive-Compulsive Disorder
Recruiting·Phase 2·ketamine

Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

The Ketamine Research Foundation

Phantom Limb Syndrome With Pain
Recruiting·Phase 3·ketamine

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

Janssen Research & Development, LLC

Depressive Disorder, Major
Recruiting·Phase 1·psilocybin

RCT of Psilocybin-assisted CBT for Depression

University of California, Los Angeles

Major Depressive Diorder
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer

Alan Davis

Lung Non-Small Cell CarcinomaUnipolar Depression
Recruiting·Phase 2·psilocybin

Psilocybin on Brain Mechanisms of Motivation in OUD

University of Pennsylvania

Opioid Use Disorder
Recruiting·Phase 2·psilocybin

Psilocybin for Opioid Use Disorder (OUD)

NYU Langone Health

Opioid Use Disorder
Recruiting·Phase 3·psilocybin

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

Cybin IRL Limited

Major Depressive Disorder (MDD)Depression in AdultsDepression - Major Depressive Disorder+3 more
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.