129 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 145–192 of 284 trials
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin Microdosing on Cognition, Mood and Quality of Life
Yale University
Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder
Indiana University
Treatment Resistant DepressionSubstance Use Disorders
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)
NYU Langone Health
IBS - Irritable Bowel Syndrome
Not Yet Recruiting·Phase 2·psilocybin
Study of Psilocybin Under Anesthesia Controlled by EEG
Stanford University
Major Depression
Not Yet Recruiting·Phase 2·psilocybin
Group Retreat Psilocybin Therapy for Healthcare Clinicians With Loss of Meaning in Their Work and Symptoms of Depression
University of Washington
DepressionAnxiety
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy as a Treatment for Depression
Washington University School of Medicine
Depression
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy
Emory University
PTSD
Not Yet Recruiting·Phase 2·psilocybin
Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy
Kyle Greenway
Treatment-Resistant Major Depressive Disorder
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin AsSisted pSychotherapy for the treatmENt of Gambling disordER : a Pilot Study
Nantes University Hospital
Gambling Disorder
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder
Centre for Addiction and Mental Health
Major Depressive Disorder (MDD)Alcohol Use Disorder (AUD)
Not Yet Recruiting·Phase 2·psilocybin
Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter
NYU Langone Health
Stuttering
Recruiting·Phase 1·psilocybin
Psilocybin Efficacy With or Without Pimavanserin Pretreatment
Johns Hopkins University
Mood (Psychological Function)Well BeingMood+1 more
Recruiting·Phase 2·psilocybin
Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
NYU Langone Health
Alcohol Use Disorder
Recruiting·Phase 1·psilocybin
Psilocybin as a Novel Therapy for Residual Anhedonia
NYU Langone Health
AnhedoniaEmotional Blunting
Recruiting·Phase 2·psilocybin
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
COMPASS Pathways
PTSD - Post Traumatic Stress DisorderPTSDPTSD Symptoms+1 more
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for Intergenerational Trauma
Rachel Yehuda
Psychological StressDepressionAnxiety
Recruiting·Early Phase 1·psilocybin
Psilocybin Administration With 5-HT1a Blockade
Johns Hopkins University
Psychedelic Effects in Healthy Volunteers
Recruiting·Phase 1·psilocybin
Psilocybin to Treat Depression in Spinal Cord Injury
James J. Peters Veterans Affairs Medical Center
Spinal Cord InjuryDepression - Major Depressive DisorderVeteran
Recruiting·Phase 3·psilocybin
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
VA Office of Research and Development
Major Depression
Recruiting·Phase 2·psilocybin
Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa
Region Skane
Anorexia Nervosa
Recruiting·Early Phase 1·psilocybin
Psilocybin as a Treatment for Chronic Pain in Smokers
Yale University
Smokers With Chronic Pain
Recruiting·Phase 2·psilocybin
Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression
Centre for Addiction and Mental Health
Treatment-Resistant Depression
Recruiting·Phase 2·psilocybin
Mindfulness-based Psilocybin Therapy for PTSD
Anthony P King
Post Traumatic Stress DisorderDepression - Major Depressive Disorder
Recruiting·Phase 2·psilocybin
The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease
Yale University
DepressionParkinson's Disease (PD)
Recruiting·Phase 3·psilocybin
Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms
Centre Hospitalier Universitaire de Nīmes
Alcohol Use DisorderDepressive SympotomsPsilocybin
Recruiting·Phase 2·psilocybin
Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)
Centre Hospitalier St Anne
Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder
Lakshmi N Yatham
Bipolar II Depression
Recruiting·Phase 1·psilocybin
A Study of Psychedelics in Healthy Older Adults With Low Well-being
Jennifer Mitchell
Anhedonia in Healthy VolunteersOlder Adults (50-90 Years)
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD
Unity Health Toronto
Post Traumatic Stress DisorderPTSDChronic PTSD
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD
Sunstone Medical
Post Traumatic Stress DisorderPTSD
Recruiting·Phase 1·psilocybin
Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.
Francisco A Moreno
Obsessive-Compulsive Disorder
Recruiting·Phase 2·psilocybin
Subjective Experience Following Psilocybin
University of Calgary
Investigating the Importance of the Subjective Psychedelic Experience
Recruiting·Phase 1·psilocybin
Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder
University of New Mexico
PTSD
Recruiting·Phase 1·psilocybin
Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer
Gustavo Vazquez
DemoralizationSafety
Recruiting·Phase 1·psilocybin
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
Healthy VolunteerOlder Adults (65-85 Years)
Recruiting·Early Phase 1·psilocybin
Psilocybin for Prolonged Grief Disorder
University of Virginia
Prolonged Grief Disorder
Recruiting·Phase 1·psilocybin
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
Johns Hopkins University
StrokeChronic StrokeIntracerebral Haemorrhage+9 more
Recruiting·Phase 3·psilocybin
Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)
Bruyère Health Research Institute.
Psychological Distress
Recruiting·Phase 1·psilocybin
RCT of Psilocybin-assisted CBT for Depression
University of California, Los Angeles
Major Depressive Diorder
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer
Alan Davis
Lung Non-Small Cell CarcinomaUnipolar Depression
Recruiting·Phase 2·psilocybin
Psilocybin on Brain Mechanisms of Motivation in OUD
University of Pennsylvania
Opioid Use Disorder
Recruiting·Phase 2·psilocybin
Psilocybin for Opioid Use Disorder (OUD)
NYU Langone Health
Opioid Use Disorder
Recruiting·Phase 3·psilocybin
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Cybin IRL Limited
Major Depressive Disorder (MDD)Depression in AdultsDepression - Major Depressive Disorder+3 more
Recruiting·Phase 1·psilocybin
Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects
Medical University of Vienna
Depression - Major Depressive DisorderAnhedonia
Recruiting·Phase 1·psilocybin
Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults
University of California, Berkeley
Aging
Recruiting·Phase 2·psilocybin
Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
University of British Columbia
Opioid DependenceChronic Pain
Recruiting·Phase 2·psilocybin
Wellcome Leap Psilocybin for OUD
Anna Rose Childress, Ph.D.
Opioid Use Disorder
Recruiting·Early Phase 1·psilocybin
PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm
Imperial College London
Self Harm
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.