131 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 145–192 of 290 trials
Not Yet Recruiting·Early Phase 1·psilocybin

Psilocybin Microdosing on Cognition, Mood and Quality of Life

Yale University

Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence

University of Calgary

Post Traumatic Stress Disorder PTSDIntimate Partner Violence (IPV)
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer: A Randomized Controlled Trial

University Health Network, Toronto

Advanced CancerStage IV Solid Tumor CancerStage IV Sarcoma of Bone+3 more
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin for Treatment of OCD-2

Francisco A Moreno

Obsessive - Compulsive Disorder
Not Yet Recruiting·Phase 1·psilocybin

The Effects of Psilocybin in Healthy Volunteers: Psychological, Biochemical and Electrophysiological Biomarkers.

Gabriella Gobbi

Healthy ParticipantsPlacebo - ControlPsilocybin
Not Yet Recruiting·Phase 1·psilocybin

The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function

Manoj Doss

Healthy
Not Yet Recruiting·Phase 1·psilocybin

The Effects of Psilocybin on Social Connectedness

Yale University

LonelinessGrief
Not Yet Recruiting·Early Phase 1·psilocybin

Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)

NYU Langone Health

IBS - Irritable Bowel Syndrome
Not Yet Recruiting·Phase 2·psilocybin

Study of Psilocybin Under Anesthesia Controlled by EEG

Stanford University

Major Depression
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy as a Treatment for Depression

Washington University School of Medicine

Depression
Not Yet Recruiting·Phase 2·psilocybin

Group Retreat Psilocybin Therapy for Healthcare Clinicians With Loss of Meaning in Their Work and Symptoms of Depression

University of Washington

DepressionAnxiety
Not Yet Recruiting·Phase 2·psilocybin

Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy

Kyle Greenway

Treatment-Resistant Major Depressive Disorder
Not Yet Recruiting·Phase 2·psilocybin

Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter

NYU Langone Health

Stuttering
Recruiting·Phase 2·psilocybin

Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin

National Institute on Aging (NIA)

Alzheimer's Disease
Recruiting·Phase 1·psilocybin

Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility Study

Oregon Health and Science University

Chronic Pelvic Pain
Recruiting·Phase 1·psilocybin

Psilocybin for Amblyopia - Targeting Critical Periods in Humans

Johns Hopkins University

Amblyopia
Recruiting·Phase 1·psilocybin

Pilot Study on the Effects of Psilocybin on Belief Updating and Insight Formation

Brown University

Phase I
Recruiting·Phase 1·psilocybin

Psilocybin Efficacy With or Without Pimavanserin Pretreatment

Johns Hopkins University

Mood (Psychological Function)Well BeingMood+1 more
Recruiting·Phase 2·psilocybin

Psilocybin AsSisted pSychotherapy for the treatmENt of Gambling disordER : a Pilot Study

Nantes University Hospital

Gambling Disorder
Recruiting·Phase 2·psilocybin

Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

COMPASS Pathways

PTSD - Post Traumatic Stress DisorderPTSDPTSD Symptoms+1 more
Recruiting·Phase 2·psilocybin

Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD

NYU Langone Health

Alcohol Use Disorder
Recruiting·Phase 2·psilocybin

Mindfulness-based Psilocybin Therapy for PTSD

Anthony P King

Post Traumatic Stress DisorderDepression - Major Depressive Disorder
Recruiting·Phase 1·psilocybin

Psilocybin as a Novel Therapy for Residual Anhedonia

NYU Langone Health

AnhedoniaEmotional Blunting
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Intergenerational Trauma

Rachel Yehuda

Psychological StressDepressionAnxiety
Recruiting·Early Phase 1·psilocybin

Psilocybin Administration With 5-HT1a Blockade

Johns Hopkins University

Psychedelic Effects in Healthy Volunteers
Recruiting·Phase 1·psilocybin

Psilocybin to Treat Depression in Spinal Cord Injury

James J. Peters Veterans Affairs Medical Center

Spinal Cord InjuryDepression - Major Depressive DisorderVeteran
Recruiting·Phase 3·psilocybin

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

VA Office of Research and Development

Major Depression
Recruiting·Phase 2·psilocybin

Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa

Region Skane

Anorexia Nervosa
Recruiting·Phase 2·psilocybin

The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease

Yale University

DepressionParkinson's Disease (PD)
Recruiting·Early Phase 1·psilocybin

Psilocybin as a Treatment for Chronic Pain in Smokers

Yale University

Smokers With Chronic Pain
Recruiting·Phase 2·psilocybin

Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression

Centre for Addiction and Mental Health

Treatment-Resistant Depression
Recruiting·Phase 2·psilocybin

Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)

Centre Hospitalier St Anne

Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)
Recruiting·Phase 3·psilocybin

Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms

Centre Hospitalier Universitaire de Nīmes

Alcohol Use DisorderDepressive SympotomsPsilocybin
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder

Lakshmi N Yatham

Bipolar II Depression
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy

Emory University

PTSD
Recruiting·Phase 1·psilocybin

A Study of Psychedelics in Healthy Older Adults With Low Well-being

Jennifer Mitchell

Anhedonia in Healthy VolunteersOlder Adults (50-90 Years)
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD

Sunstone Medical

Post Traumatic Stress DisorderPTSD
Recruiting·Phase 1·psilocybin

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

Francisco A Moreno

Obsessive-Compulsive Disorder
Recruiting·Phase 2·psilocybin

Subjective Experience Following Psilocybin

University of Calgary

Investigating the Importance of the Subjective Psychedelic Experience
Recruiting·Phase 1·psilocybin

Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder

University of New Mexico

PTSD
Recruiting·Phase 1·psilocybin

Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer

Gustavo Vazquez

DemoralizationSafety
Recruiting·Phase 1·psilocybin

Safety and Tolerability Trial of Psilocybin in Healthy Older Adults

University of Colorado, Denver

Healthy VolunteerOlder Adults (65-85 Years)
Recruiting·Early Phase 1·psilocybin

Psilocybin for Prolonged Grief Disorder

University of Virginia

Prolonged Grief Disorder
Recruiting·Phase 2·psilocybin

Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder

Centre for Addiction and Mental Health

Major Depressive Disorder (MDD)Alcohol Use Disorder (AUD)
Recruiting·Phase 1·psilocybin

Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

Johns Hopkins University

StrokeChronic StrokeIntracerebral Haemorrhage+9 more
Recruiting·Phase 3·psilocybin

Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)

Bruyère Health Research Institute.

Psychological Distress
Recruiting·Phase 1·psilocybin

RCT of Psilocybin-assisted CBT for Depression

University of California, Los Angeles

Major Depressive Diorder
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer

Alan Davis

Lung Non-Small Cell CarcinomaUnipolar Depression
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.