Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression
VA Office of Research and Development
A Phase 2A Trial of DT402 for Autism Spectrum Disorder
Definium Therapeutics US, Inc.
Ketamine Sedation in the ICU (KANINE) RCT
McMaster University
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
ACADIA Pharmaceuticals Inc.
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
Texas Tech University Health Sciences Center
Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects
Medical University of Vienna
Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults
University of California, Berkeley
Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
University of British Columbia
PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm
Imperial College London
Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant Depression
Hospital Universitari Vall d'Hebron Research Institute
Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)
Johns Hopkins University
Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension
University General Hospital of Patras
MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)
Carolyn Rodriguez
Mapping Ibogaine Neural Dynamics in Opioid Use Disorder
University of California, Irvine
MDMA in Borderline Personality Disorder
Yale University
Analgosedation With Ketamine, Nalbuphine, or Dexmedetomidine for Suture Removal in Children After Cleft Surgery
University Medical Centre Ljubljana
Pain Control Alternatives in Pediatric Patients With Distal Radius Fractures
State University of New York at Buffalo
PRoMiSS: Psilocybin and the Role of Music in Set and Setting
Johns Hopkins University
The RECAP2 Study: Midazolam and Psilocybin
University of Wisconsin, Madison
Antidepressant Response of DMT Masked With Propofol
University Hospital, Basel, Switzerland
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
Yale University
Mindfulness-Assisted Psychedelic Therapy
University of Southern California
Magnesium and Cramping
Corewell Health East
A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression
Juliana Zambrano, MD, MPH
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers of Patients With Advanced Cancer
University Health Network, Toronto
Ketamine Augmentation of ECT in Treatment-Resistant Depression
Università Vita-Salute San Raffaele
Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality
The University of Texas Health Science Center, Houston
Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD
Northwestern University
Psilocybin Therapy for Psychological Distress in Palliative Patients
University Medical Center Groningen
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial
University of Iowa
Dose Optimization of MDMA-Assisted Therapy for PTSD
Bronx VA Medical Center
Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder
Dr. med. Marcus Herdener
Working Mechanisms and Effectiveness of IV Ketamine-assisted Psychotherapy on Depression in TRD Clients
Senz
Music as an Adjunct to Ketamine Therapy for Chronic Pain
McGill University
A Randomized Neuroimaging Trial of Psilocybin in Depression
Sunnybrook Health Sciences Centre
Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
Yale University
Treatment of Persisting Symptoms After Concussion With Psilocybin Assisted Therapy
University of Calgary
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
M.D. Anderson Cancer Center
Mechanistic Studies of Psilocybin in Headache Disorders
Yale University
Safety, Tolerability, and Preliminary Efficacy of Psilocybin Oral Solution in Adults With Generalized Anxiety Disorder
Claudio N Soares
Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments
Neuronetics
Investigation to Understand and Optimize Psilocybin
Charles Raison
ACT_for Alcohol Use Disorder and Depression
Centre hospitalier de l'Université de Montréal (CHUM)
Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery
University of Utah
Role of the Serotonin 2A Receptor in Psilocybin-induced Altered States of Consciousness
University Hospital, Basel, Switzerland
Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)
Centre for Addiction and Mental Health
LSD to Improve Cluster Headache Impact Trial
Radboud University Medical Center
Best Hypnotic Drug Choice for Rapid Sequence Induction in the Operating Room
Nantes University Hospital
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.