Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Psilocybin on Brain Mechanisms of Motivation in OUD
University of Pennsylvania
Psilocybin for Opioid Use Disorder (OUD)
NYU Langone Health
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Cybin IRL Limited
Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects
Medical University of Vienna
Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults
University of California, Berkeley
Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
University of British Columbia
PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm
Imperial College London
Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)
Johns Hopkins University
PRoMiSS: Psilocybin and the Role of Music in Set and Setting
Johns Hopkins University
The RECAP2 Study: Midazolam and Psilocybin
University of Wisconsin, Madison
Mindfulness-Assisted Psychedelic Therapy
University of Southern California
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers of Patients With Advanced Cancer
University Health Network, Toronto
Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality
The University of Texas Health Science Center, Houston
Psilocybin Therapy for Psychological Distress in Palliative Patients
University Medical Center Groningen
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial
University of Iowa
Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
Yale University
A Randomized Neuroimaging Trial of Psilocybin in Depression
Sunnybrook Health Sciences Centre
Treatment of Persisting Symptoms After Concussion With Psilocybin Assisted Therapy
University of Calgary
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
M.D. Anderson Cancer Center
Mechanistic Studies of Psilocybin in Headache Disorders
Yale University
Safety, Tolerability, and Preliminary Efficacy of Psilocybin Oral Solution in Adults With Generalized Anxiety Disorder
Claudio N Soares
Investigation to Understand and Optimize Psilocybin
Charles Raison
Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)
Centre for Addiction and Mental Health
Role of the Serotonin 2A Receptor in Psilocybin-induced Altered States of Consciousness
University Hospital, Basel, Switzerland
Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis
Johns Hopkins University
Psilocybin for Methamphetamine Addiction
Kevin Murnane
Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in Healthy Participants
University Hospital, Basel, Switzerland
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
Centre for Addiction and Mental Health
Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN
Unity Health Toronto
Digital Intervention for Psychedelic Preparation (DIPP): Comparing Meditation and Music-Based Programs
University College, London
Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder
Icahn School of Medicine at Mount Sinai
Investigation of Psychedelic Effects in Psychoactive Substances
Johns Hopkins University
State-Funded Trial Assessing Recovery and Long-Term Impact of Guided Psilocybin for Healing Trauma
Baylor College of Medicine
The ENHANCE Study: taVNS and Psilocybin
University of Wisconsin, Madison
Pragmatic Trial of Psilocybin Therapy in Palliative Care
Charles S. Grob, M.D.
Psilocybin-Assisted Therapy for Physician Well-Being and Burnout
University of California, San Diego
Psilocybin rTMS for Treatment Resistant Depression
University of Texas at Austin
Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence
University of Colorado, Denver
Study of Psilocybin for Anorexia in Young Adults
Marissa Raymond-Flesch, MD, MPH
Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers
Robin Carhart-Harris, PhD, MA
Open-Label Psilocybin Study in Transdiagnostic Population
Yale University
The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder
Sharmin Ghaznavi
Psilocybin Therapy for Depression in Parkinson's Disease
Joshua Woolley, MD, PhD
Psilocybin for Hospitalized Patients with Treatment-resistant Depression
University Hospital, Ghent
The Impact of Psilocybin on Pain in Fibromyalgia Patients
Maastricht University
Psilocybin in Chronic Low Back Pain and Depression
Johns Hopkins University
Cancer Related Major Depression Treated With a Single Dose of Psilocybin
Section for Affective Disorders; Northern Stockholm Psychiatry
Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy
M.D. Anderson Cancer Center
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.