Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis
Johns Hopkins University
Understanding and Treating Suicidal Ideation With Ketamine
The Royal's Institute of Mental Health Research
Psilocybin for Methamphetamine Addiction
Kevin Murnane
Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in Healthy Participants
University Hospital, Basel, Switzerland
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
Centre for Addiction and Mental Health
Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans
Deepak C. D'Souza
Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN
Unity Health Toronto
Digital Intervention for Psychedelic Preparation (DIPP): Comparing Meditation and Music-Based Programs
University College, London
MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
Stephen Robert Marder
Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine
Assistance Publique - Hôpitaux de Paris
Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder
Icahn School of Medicine at Mount Sinai
Intravenous Ketamine for Treatment-Resistant Depression
Mayo Clinic
MDMA-assisted Cognitive Processing Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress Disorder
Patricia Suppes
Investigation of Psychedelic Effects in Psychoactive Substances
Johns Hopkins University
State-Funded Trial Assessing Recovery and Long-Term Impact of Guided Psilocybin for Healing Trauma
Baylor College of Medicine
The ENHANCE Study: taVNS and Psilocybin
University of Wisconsin, Madison
Plasma Oxytocin Changes in Response to Low-dose MDMA vs. Placebo in Patients With Arginine Vasopressin Deficiency and Healthy Controls
University Hospital, Basel, Switzerland
PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study
Yale University
Ketamine for Combined Depression and Alcohol Use Disorder
University Hospital of North Norway
Pragmatic Trial of Psilocybin Therapy in Palliative Care
Charles S. Grob, M.D.
Psilocybin-Assisted Therapy for Physician Well-Being and Burnout
University of California, San Diego
Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression
Icahn School of Medicine at Mount Sinai
Psilocybin rTMS for Treatment Resistant Depression
University of Texas at Austin
Ketamine Sedation As Neuroprotective Agent Following Out-of-hospital Cardiac Arrest
Christian Hassager
Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose Ketamine
Insel Gruppe AG, University Hospital Bern
Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence
University of Colorado, Denver
Study of Psilocybin for Anorexia in Young Adults
Marissa Raymond-Flesch, MD, MPH
MDMA-Assisted CBCT for PTSD vs CBCT RCT
Remedy
Cognitive Training as an Adjunct to Ketamine in Real-world Clinics
University of Pittsburgh
Veteran's Perceptions of Ketamine-Assisted Psychotherapy for Depression and End-of-Life
Albany Research Institute, Inc.
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
National Institute of Mental Health (NIMH)
Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients
Assistance Publique - Hôpitaux de Paris
Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers
Robin Carhart-Harris, PhD, MA
Open-Label Psilocybin Study in Transdiagnostic Population
Yale University
Nebulized Ketamine for the Treatment of Major Depressive Disorder
Theresa Jacob, PhD, MPH
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
Margaux M. Salas, PhD
(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain
Rush University Medical Center
The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder
Sharmin Ghaznavi
Tolerability of MDMA in Schizophrenia
Anya Bershad, MD, PhD
Imaging Depression in Parkinson's Disease
Yale University
The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
Dr. Inge Winter
Psilocybin Therapy for Depression in Parkinson's Disease
Joshua Woolley, MD, PhD
Low-Dose Ketamine Infusion During Burn Wound Care
University of Tennessee
Lysergic Acid Diethylamide (LSD) in Palliative Care
University Hospital, Basel, Switzerland
Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease
University of Rochester
Psilocybin for Hospitalized Patients with Treatment-resistant Depression
University Hospital, Ghent
Effect of Opioid-Free vs Opioid-Based Anesthesia on Postoperative Pain and Emergence Agitation in Children Undergoing Cleft Surgery
Iva Smiljanić
Belief Updating in Treatment Resistant Depression
Assistance Publique - Hôpitaux de Paris
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.