410 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 1–48 of 410 trials
Enrolling by Invitation·N/A·ketamine
Intramuscular Ketamine for Suicidal Patients in the Evanston Hospital Emergency Department for Suicidal Distress
Endeavor Health
SuicidalSuicidal IdeationSuicidal Ideation and Behavior+1 more
Enrolling by Invitation·Phase 2·ketamine
Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study
University of Michigan
HealthyCovert Consciousness
Enrolling by Invitation·N/A·psilocybin
Psilocybin-Assisted Group Integration Psychotherapy for Treatment-Resistant Depression
Joshua Rosenblat
Treatment-resistant Depression (TRD)
Enrolling by Invitation·Phase 4·ketamine
The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.
University of Missouri-Columbia
Spine Surgery
Enrolling by Invitation·N/A·ketamine
Psychotherapy Combined With Intranasal Esketamine for the Treatment of Suicidal Ideation
University of California, San Diego
Suicidal Ideation
Enrolling by Invitation·N/A·psilocybin
Salivary Oxytocin as a Biomarker of Psychedelic Treatment
University of Geneva, Switzerland
Major Depressive Disorder (MDD)
Enrolling by Invitation·Phase 3·psilocybin
Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)
Cybin IRL Limited
Major Depressive Disorder
Enrolling by Invitation·Phase 2·ketamine
Ketamine Effects on Learning In Eating Disorders
Amanda Downey, MD
Anorexia NervosaAtypical Anorexia Nervosa
Enrolling by Invitation·Phase 1·psilocybin
Psilocybin With Intracranial Neural Sensing
Joshua Woolley, MD, PhD
Chronic Pain
Enrolling by Invitation·Phase 1·Other
Induction of Dreaming With EEG and Anesthesia in Healthy Adults
Stanford University
Healthy Volunteers
Enrolling by Invitation·Phase 2·MDMA
High-Intensity Inpatient MDMA-Assisted Psychotherapy for PTSD
ARQ National Psychotrauma Centre
Posttraumatic Stress Disorder (PTSD)
Enrolling by Invitation·N/A·ketamine
Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions
Psyrin Inc.
Obsessive Compulsive Disorder (OCD)Bipolar DisordersMajor Depressive Disorder+2 more
Enrolling by Invitation·Phase 2·MDMA
MDMA Plus Exposure Therapy for PTSD
Emory University
PTSD
Enrolling by Invitation·N/A·ketamine
Long Term Follow Up KET-PD
Yale University
Parkinson's DiseaseDepression
Enrolling by Invitation·Phase 4·ketamine
Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan
Brigham and Women's Hospital
Acute Suicidal Depression (ASD)
Enrolling by Invitation·N/A·ketamine
Prediction of REsponse to Depression Interventions Using Clinical and TD-fNIRS Measurements
Kernel
DepressionMajor Depressive Disorder
Enrolling by Invitation·N/A·Other
Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES
University of Kansas Medical Center
AnesthesiaTubal Ligation
Enrolling by Invitation·N/A·psilocybin
The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training
Felix Mueller
Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
Enrolling by Invitation·N/A·ketamine
Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)
Medical University of Gdansk
Major Depressive DisorderPost Traumatic Stress DisorderObsessive-Compulsive Disorder+3 more
Enrolling by Invitation·N/A·ketamine
Observational Study of Ketamine Infusions for the Treatment of Chronic Pain
Theresa Lii
Chronic Pain
Enrolling by Invitation·N/A·ketamine
Long-term Pain Modulation by Intravenous Esketamine in CRPS
Erasmus Medical Center
Complex Regional Pain SyndromesCRPS (Complex Regional Pain Syndromes)
Enrolling by Invitation·N/A·ketamine
Effect of Ketamine and Etomidate During RSI on Long Term Outcomes
Vanderbilt University Medical Center
Post-Traumatic Stress DisorderAcute Respiratory Failure
Enrolling by Invitation·Phase 3·Other
GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
Hospital for Special Surgery, New York
Lumbar Disc HerniationLumbar Disc DiseaseLumbar Radiculopathy
Enrolling by Invitation·Phase 4·ketamine
Ketamine Infusion for Neuropathic Pain in Brachial Plexus Injuries
Mayo Clinic
Brachial Plexus Injury
Enrolling by Invitation·N/A·ketamine
Safety and Efficacy of Ketamine Intravenous Infusions in the Treatment of Fibromyalgia
Wilderman Medical Clinic
Fibromyalgia
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin After Trauma Surgery for Pain
Trent Emerick
Pain ManagementPostoperative Pain
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin for Methamphetamine Use Disorder
Peter Hendricks
Methamphetamine Use Disorder
Not Yet Recruiting·Phase 2·psilocybin
Group PACBT for Depression
University of California, Los Angeles
Depression - Major Depressive DisorderPsilocybinCognitive Behavioral Therapy
Not Yet Recruiting·N/A·Other
Hemodynamic Responses to Laryngoscopy and Tracheal Intubation
Assiut University
Hemodynamic Response to Laryngoscopy and Tracheal Intubation
Not Yet Recruiting·Phase 2·LSD
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of PLX-200 in Pediatric Patients (Master Protocol)
Polaryx Therapeutics, Inc.
Lysosomal Storage DisordersSandhoff DiseaseKrabbe Disease+2 more
Not Yet Recruiting·Phase 2·ketamine
Electrophysiologic Mechanisms of Ketamine Antidepressant Response
Emory University
EpilepsyDepressive Symptoms
Not Yet Recruiting·Phase 1·psilocybin
MLS101 Study in PMDD
MycoMedica Life Sciences PBC
Premenstrual Dysphoric Disorder ( PMDD)PMDD
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Psychotherapy for Veterans With PTSD
ARQ National Psychotrauma Centre
Posttraumatic Stress Disorder (PTSD)
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life
Charles Raison
AgingLongevityBiomarkers of Aging
Not Yet Recruiting·Phase 2·psilocybin
NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy
M.D. Anderson Cancer Center
PsilocybinNeuropathy
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin Therapy for Methamphetamine Use Disorder and HIV
Nicky Mehtani, MD, MPH
Methamphetamine Use DisorderHuman Immunodeficiency Virus (HIV)
Not Yet Recruiting·Phase 1·psilocybin
Pilot Study on the Effects of Psilocybin on Belief Updating and Insight Formation
Brown University
Phase I
Not Yet Recruiting·Phase 2·MDMA
MDMA-AT for PTSD in Young Adults With Childhood Trauma
Jenna M. Traynor
Posttraumatic Stress Disorder (PTSD)
Not Yet Recruiting·Phase 2·ketamine
Adjunctive Oral KET-AD Capsules in Treatment Resistant Bipolar Depression
Neurocentrx Pharma Pty Ltd
Treatment Resistant Bipolar Depression
Not Yet Recruiting·Phase 2·psilocybin
MB-PAT for Demoralization in Advanced Cancer ('PAT-MIND') Trial
University of Calgary
Advanced CancerDemoralizationExistential Distress+1 more
Not Yet Recruiting·Phase 3·ketamine
KetAmine and Recovery After Mechanical VentilAtion ( KARMA )
Assistance Publique - Hôpitaux de Paris
Critical Illness
Not Yet Recruiting·Phase 2·psilocybin
Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin
National Institute on Aging (NIA)
Alzheimer's Disease
Not Yet Recruiting·Phase 4·ketamine
Adaptive Platform Trial for Pain Management in Sickle Cell Vaso-Occlusive Crisis
Assistance Publique - Hôpitaux de Paris
Sickle Cell DiseaseVaso-occlusive Crisis
Not Yet Recruiting·Phase 4·ketamine
Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal Thoughts
New York State Psychiatric Institute
Major Depressive Disorder (MDD)
Not Yet Recruiting·Phase 1·ketamine
Oral and Sublingual Ketamine
Western University, Canada
Major Depression Severe
Not Yet Recruiting·Phase 2·MDMA
Clinical Trial of MDMA-Assisted Therapy for Military Service Members With Posttraumatic Stress Disorder
U.S. Army Medical Research and Development Command
PTSDPost Traumatic Stress Disorder PTSDPost Traumatic Stress Disorder
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence
University of Calgary
Post Traumatic Stress Disorder PTSDIntimate Partner Violence (IPV)
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility Study
Oregon Health and Science University
Chronic Pelvic Pain
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Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.