347 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 1–48 of 347 trials
Enrolling by Invitation·N/A·ketamine
Intramuscular Ketamine for Suicidal Patients in the Evanston Hospital Emergency Department for Suicidal Distress
Endeavor Health
SuicidalSuicidal IdeationSuicidal Ideation and Behavior+1 more
Enrolling by Invitation·Phase 2·ketamine
Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study
University of Michigan
HealthyCovert Consciousness
Enrolling by Invitation·N/A·psilocybin
Psilocybin-Assisted Group Integration Psychotherapy for Treatment-Resistant Depression
Joshua Rosenblat
Treatment-resistant Depression (TRD)
Enrolling by Invitation·Phase 4·ketamine
The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.
University of Missouri-Columbia
Spine Surgery
Enrolling by Invitation·N/A·ketamine
Psychotherapy Combined With Intranasal Esketamine for the Treatment of Suicidal Ideation
University of California, San Diego
Suicidal Ideation
Enrolling by Invitation·N/A·psilocybin
Salivary Oxytocin as a Biomarker of Psychedelic Treatment
University of Geneva, Switzerland
Major Depressive Disorder (MDD)
Enrolling by Invitation·Phase 3·psilocybin
Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)
Cybin IRL Limited
Major Depressive Disorder
Enrolling by Invitation·Phase 2·ketamine
Ketamine Effects on Learning In Eating Disorders
Amanda Downey, MD
Anorexia NervosaAtypical Anorexia Nervosa
Enrolling by Invitation·Phase 1·psilocybin
Psilocybin With Intracranial Neural Sensing
Joshua Woolley, MD, PhD
Chronic Pain
Enrolling by Invitation·Phase 2·MDMA
High-Intensity Inpatient MDMA-Assisted Psychotherapy for PTSD
ARQ National Psychotrauma Centre
Posttraumatic Stress Disorder (PTSD)
Enrolling by Invitation·N/A·ketamine
Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions
Psyrin Inc.
Obsessive Compulsive Disorder (OCD)Bipolar DisordersMajor Depressive Disorder+2 more
Enrolling by Invitation·Phase 2·MDMA
MDMA Plus Exposure Therapy for PTSD
Emory University
PTSD
Enrolling by Invitation·Phase 4·ketamine
Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan
Brigham and Women's Hospital
Acute Suicidal Depression (ASD)
Enrolling by Invitation·N/A·ketamine
Prediction of REsponse to Depression Interventions Using Clinical and TD-fNIRS Measurements
Kernel
DepressionMajor Depressive Disorder
Enrolling by Invitation·N/A·psilocybin
The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training
Felix Mueller
Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
Enrolling by Invitation·N/A·ketamine
Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)
Medical University of Gdansk
Major Depressive DisorderPost Traumatic Stress DisorderObsessive-Compulsive Disorder+3 more
Enrolling by Invitation·N/A·ketamine
Observational Study of Ketamine Infusions for the Treatment of Chronic Pain
Theresa Lii
Chronic Pain
Enrolling by Invitation·N/A·ketamine
Long-term Pain Modulation by Intravenous Esketamine in CRPS
Erasmus Medical Center
Complex Regional Pain SyndromesCRPS (Complex Regional Pain Syndromes)
Enrolling by Invitation·N/A·ketamine
Effect of Ketamine and Etomidate During RSI on Long Term Outcomes
Vanderbilt University Medical Center
Post-Traumatic Stress DisorderAcute Respiratory Failure
Enrolling by Invitation·Phase 4·ketamine
Ketamine Infusion for Neuropathic Pain in Brachial Plexus Injuries
Mayo Clinic
Brachial Plexus Injury
Enrolling by Invitation·N/A·ketamine
Safety and Efficacy of Ketamine Intravenous Infusions in the Treatment of Fibromyalgia
Wilderman Medical Clinic
Fibromyalgia
Not Yet Recruiting·Phase 4·ketamine
Perioperative Esketamine Safety and Efficacy in Reducing Postoperative ENDometriosis PAIN (the ENDPAIN Trial): a Randomized Controlled Trial.
Region Skane
Endometriosis
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin After Trauma Surgery for Pain
Trent Emerick
Pain ManagementPostoperative Pain
Not Yet Recruiting·Phase 1·ibogaine
Medically Supervised Ibogaine With 12-Month Digital Recovery Support for Opioid Use Disorder
Clive Michelsen
Opioid Use DisorderOpioid WithdrawalSubstance Use Disorders
Not Yet Recruiting·Phase 1·psilocybin
The Impact of Dose on the Impairing, Intoxicating, and Abuse-Related Effects of Psilocybin
Johns Hopkins University
Psilocybin Intoxication
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder
Indiana University
Treatment Resistant DepressionSubstance Use Disorders
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin for Methamphetamine Use Disorder
Peter Hendricks
Methamphetamine Use Disorder
Not Yet Recruiting·Phase 1·psilocybin
Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study
University of Wisconsin, Madison
Well-Being, PsychologicalPsychedelic Experiences
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin FCR Early-Stage Breast Cancer
NYU Langone Health
Early-stage Breast CancerFear of Cancer RecurrenceAnxiety+1 more
Not Yet Recruiting·Phase 2·ketamine
Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder
University Hospital, Toulouse
Infusion of Ketamine in Severe Borderline Personality DisorderBorderline Personality Disorder (BPD)
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin for Depression in Veterans
VA Office of Research and Development
Major Depression
Not Yet Recruiting·N/A·ketamine
Acceptance and Committment Therapy Combined With Ketamine in Difficult-to-Treat Depression.
University of British Columbia
Major Depressive Disorder (MDD)
Not Yet Recruiting·Phase 2·psilocybin
Effects of Psilocybin on Craving in Nicotine Dependence
University of British Columbia
Nicotine Dependence
Not Yet Recruiting·Phase 2·psilocybin
Group PACBT for Depression
University of California, Los Angeles
Depression - Major Depressive DisorderPsilocybinCognitive Behavioral Therapy
Not Yet Recruiting·Phase 2·psilocybin
Assessing of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
University of New Mexico
PTSDPTSD - Post Traumatic Stress DisorderMajor Depression+1 more
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
Roswell Park Cancer Institute
Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Not Yet Recruiting·Phase 4·ketamine
Effect of Low-Dose Esketamine Combined With Dexmedetomidine on the Incidence of Chronic Postsurgical Pain in Patients Undergoing Pancreatic Surgery
Tianjin Medical University Cancer Institute and Hospital
Chronic Pain, Postoperative
Not Yet Recruiting·Phase 2·LSD
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of PLX-200 in Pediatric Patients (Master Protocol)
Polaryx Therapeutics, Inc.
Lysosomal Storage DisordersSandhoff DiseaseKrabbe Disease+2 more
Not Yet Recruiting·Phase 1·LSD
Shortened LSD Intervention for Major Depressive Disorder
Johns Hopkins University
Major Depression ModerateMajor Depression SevereMajor Depression
Not Yet Recruiting·Phase 1·psilocybin
ADEPT Psilocybin-Assisted Therapy With DBT for Borderline Personality Disorder
University of Minnesota
Borderline Personality DisorderBorderline Personality PathologyDepressive Symptoms+2 more
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Psychotherapy for Veterans With PTSD
ARQ National Psychotrauma Centre
Posttraumatic Stress Disorder (PTSD)
Not Yet Recruiting·Phase 2·ketamine
Electrophysiologic Mechanisms of Ketamine Antidepressant Response
Emory University
EpilepsyDepressive Symptoms
Not Yet Recruiting·Phase 1·psilocybin
MLS101 Study in PMDD
MycoMedica Life Sciences PBC
Premenstrual Dysphoric Disorder ( PMDD)PMDD
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
Yale University
Chronic Low Back Pain (CLBP)Physical TherapyPsilocybin
Not Yet Recruiting·Phase 2·ketamine
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
University of Rochester
Treatment Resistant Depression (TRD)Chronic Pain
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life
Charles Raison
AgingLongevityBiomarkers of Aging
Not Yet Recruiting·Phase 2·ketamine
Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse
University of Oklahoma
Head and Neck Cancer
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
Brigham and Women's Hospital
Alcohol Use Disorder
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Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.