415 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 913–960 of 1750 trials
Enrolling by Invitation·Phase 4·ketamine
Ketamine Infusion for Neuropathic Pain in Brachial Plexus Injuries
Mayo Clinic
Brachial Plexus Injury
Enrolling by Invitation·N/A·ketamine
Safety and Efficacy of Ketamine Intravenous Infusions in the Treatment of Fibromyalgia
Wilderman Medical Clinic
Fibromyalgia
No Longer Available·N/A·MDMA
A Multi-site Expanded Access Program for MDMA-assisted Psychotherapy for Patients With Treatment-resistant PTSD
Resilient Pharmaceuticals
Post Traumatic Stress Disorder
Not Yet Recruiting·Phase 2·psilocybin
Group PACBT for Depression
University of California, Los Angeles
Depression - Major Depressive DisorderPsilocybinCognitive Behavioral Therapy
Not Yet Recruiting·Phase 2·LSD
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of PLX-200 in Pediatric Patients (Master Protocol)
Polaryx Therapeutics, Inc.
Lysosomal Storage DisordersSandhoff DiseaseKrabbe Disease+2 more
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life
Charles Raison
AgingLongevityBiomarkers of Aging
Not Yet Recruiting·Phase 2·psilocybin
NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy
M.D. Anderson Cancer Center
PsilocybinNeuropathy
Not Yet Recruiting·Phase 2·ketamine
Adjunctive Oral KET-AD Capsules in Treatment Resistant Bipolar Depression
Neurocentrx Pharma Pty Ltd
Treatment Resistant Bipolar Depression
Not Yet Recruiting·Phase 3·ketamine
KetAmine and Recovery After Mechanical VentilAtion ( KARMA )
Assistance Publique - Hôpitaux de Paris
Critical Illness
Not Yet Recruiting·Phase 1·ketamine
Oral and Sublingual Ketamine
Western University, Canada
Major Depression Severe
Not Yet Recruiting·Phase 2·MDMA
Clinical Trial of MDMA-Assisted Therapy for Military Service Members With Posttraumatic Stress Disorder
U.S. Army Medical Research and Development Command
PTSDPost Traumatic Stress Disorder PTSDPost Traumatic Stress Disorder
Not Yet Recruiting·Phase 4·ketamine
Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal Thoughts
New York State Psychiatric Institute
Major Depressive Disorder (MDD)
Not Yet Recruiting·Phase 2·psilocybin
Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin
National Institute on Aging (NIA)
Alzheimer's Disease
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility Study
Oregon Health and Science University
Chronic Pelvic Pain
Not Yet Recruiting·Phase 2·MDMA
MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers and First Responders
Nautilus Sanctuary
Post-Traumatic Stress DisorderAdjustment Disorders
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin for Treatment of OCD-2
Francisco A Moreno
Obsessive - Compulsive Disorder
Not Yet Recruiting·Phase 2·ketamine
Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder
University Hospital, Toulouse
Infusion of Ketamine in Severe Borderline Personality DisorderBorderline Personality Disorder (BPD)
Not Yet Recruiting·N/A·Other
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
Ente Ospedaliero Ospedali Galliera
FrailyAbdominal SurgeryPostoperative Cognitive Dysfunction (POCD)
Not Yet Recruiting·Phase 3·ketamine
Morphine or Ketamine for Analgesia
Columbia University
Abdominal PainIsolated Extremity FracturePain+1 more
Not Yet Recruiting·Phase 1·psilocybin
The Effects of Psilocybin in Healthy Volunteers: Psychological, Biochemical and Electrophysiological Biomarkers.
Gabriella Gobbi
Healthy ParticipantsPlacebo - ControlPsilocybin
Not Yet Recruiting·Phase 2·ketamine
Nebulized Ketamine Plus Standard Care vs. Standard Care Alone in Moderate to Severe Asthma Exacerbations
Oman Medical Speciality Board
Asthma AcuteAsthma AttackAsthma Exacerbations
Not Yet Recruiting·Phase 1·DMT
Neural Effects of Intravenous N,N-dimethyltryptamine (DMT)
Jon Dean
Healthy Participants Study
Not Yet Recruiting·Phase 1·psilocybin
Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study
University of Wisconsin, Madison
Well-Being, PsychologicalPsychedelic Experiences
Not Yet Recruiting·Phase 1·psilocybin
The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function
Manoj Doss
Healthy
Not Yet Recruiting·Phase 2·psilocybin
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
COMPASS Pathways
PTSD - Post Traumatic Stress DisorderPTSDPTSD Symptoms+1 more
Not Yet Recruiting·Phase 2·psilocybin
Assessing of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
University of New Mexico
PTSDPTSD - Post Traumatic Stress DisorderMajor Depression+1 more
Not Yet Recruiting·Phase 1·psilocybin
The Effects of Psilocybin on Social Connectedness
Yale University
LonelinessGrief
Not Yet Recruiting·Phase 1·LSD
Shortened LSD Intervention for Major Depressive Disorder
Johns Hopkins University
Major Depression ModerateMajor Depression SevereMajor Depression
Not Yet Recruiting·N/A·ketamine
Testing Two Doses of Nebulized Ketamine for Postoperative Sore Throat
Aswan University Hospital
Postoperative Sore Throat
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
Roswell Park Cancer Institute
Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Not Yet Recruiting·Phase 2·ketamine
Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers
National Center for Complementary and Integrative Health (NCCIH)
Healthy Volunteers
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin Microdosing on Cognition, Mood and Quality of Life
Yale University
Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI
Not Yet Recruiting·N/A·ketamine
Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.
China-Japan Friendship Hospital
Knee OsteoarthritisReplacement, KneeElective Surgical Patients+1 more
Not Yet Recruiting·Phase 4·ketamine
Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis
University of Mississippi Medical Center
Vaso-Occlusive Pain Episode in Sickle Cell DiseaseSickle Cell Disease (SCD)
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder
Indiana University
Treatment Resistant DepressionSubstance Use Disorders
Not Yet Recruiting·Phase 4·ketamine
Intraperitoneal Ketamine Versus Fentanyl as Adjuvants to Bupivacaine in Laparoscopic Cholecystectomy
Assiut University
Postoperative Pain
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence
University of Calgary
Post Traumatic Stress Disorder PTSDIntimate Partner Violence (IPV)
Not Yet Recruiting·Phase 4·Other
Examining Analgesic Synergy and Efficacy in Trauma Care
Wake Forest University Health Sciences
Opioid Use Disorder
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)
NYU Langone Health
IBS - Irritable Bowel Syndrome
Not Yet Recruiting·N/A·ketamine
Outcomes Registry After Ketamine Infusions for Chronic Pain: A Longitudinal Evaluation
Stanford University
Chronic PainKetamine
Not Yet Recruiting·Phase 3·psilocybin
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
VA Office of Research and Development
Major Depression
Not Yet Recruiting·N/A·Other
Prospective Multicentre Observational Registry of Peri-procedural Anaesthesia, Sedation and Related Medication Exposure in Patients With Brugada Syndrome
Hospital Clinic of Barcelona
Brugada Syndrome (BrS)Ventricular ArrhythmiaAnesthesia+1 more
Not Yet Recruiting·N/A·ketamine
Intra-Sessional Autonomic Arc Detection in Ketamine-Assisted Therapy for PTSD: A Signal Characterisation Pilot Study
Adriaan Dirk van der Wart
Post-Traumatic Stress Disorder
Not Yet Recruiting·N/A·ketamine
Esketamine Versus Sufentanil for Sedation in Patients Undergoing ERCP
Ren Da
Biliary Tract DiseasesProcedural Sedation and Analgesia
Not Yet Recruiting·N/A·Other
Quality of Recovery-15 After Opioid-free Versus Opioid-based General Anesthesia in Major Urological Surgery
Jagiellonian University
Postoperative RecoveryAnesthesia, GeneralAnalgesics, Opioid+1 more
Not Yet Recruiting·Phase 2·Other
Effect of Opioid-Sparing Anesthesia on Postoperative Opioid Consumption and Pain in Elderly Patients Undergoing Spine Surgery
Massachusetts General Hospital
Opoid ManagmentPain Management
Not Yet Recruiting·Phase 2·ketamine
Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study
University of Michigan
HealthyCovert Consciousness
Not Yet Recruiting·N/A·Other
Biomarker Discovery for Suicide Precision Circuit Therapeutics
Massachusetts General Hospital
Suicidal Thoughts and BehaviorsMajor Depressive Episode (MDE)
Browse by Condition
View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.