410 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 49–96 of 410 trials
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
Yale University
Chronic Low Back Pain (CLBP)Physical TherapyPsilocybin
Not Yet Recruiting·Phase 4·Other
Examining Analgesic Synergy and Efficacy in Trauma Care
Wake Forest University Health Sciences
Opioid Use Disorder
Not Yet Recruiting·Phase 2·MDMA
MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers and First Responders
Nautilus Sanctuary
Post-Traumatic Stress DisorderAdjustment Disorders
Not Yet Recruiting·N/A·ketamine
Outcomes Registry After Ketamine Infusions for Chronic Pain: A Longitudinal Evaluation
Stanford University
Chronic PainKetamine
Not Yet Recruiting·Phase 2·ketamine
Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers
National Center for Complementary and Integrative Health (NCCIH)
Healthy Volunteers
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
Roswell Park Cancer Institute
Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer: A Randomized Controlled Trial
University Health Network, Toronto
Advanced CancerStage IV Solid Tumor CancerStage IV Sarcoma of Bone+3 more
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin for Treatment of OCD-2
Francisco A Moreno
Obsessive - Compulsive Disorder
Not Yet Recruiting·Phase 3·ketamine
Morphine or Ketamine for Analgesia
Columbia University
Abdominal PainIsolated Extremity FracturePain+1 more
Not Yet Recruiting·Phase 2·ketamine
Nebulized Ketamine Plus Standard Care vs. Standard Care Alone in Moderate to Severe Asthma Exacerbations
Oman Medical Speciality Board
Asthma AcuteAsthma AttackAsthma Exacerbations
Not Yet Recruiting·Phase 1·DMT
Neural Effects of Intravenous N,N-dimethyltryptamine (DMT)
Jon Dean
Healthy Participants Study
Not Yet Recruiting·Phase 1·psilocybin
The Effects of Psilocybin in Healthy Volunteers: Psychological, Biochemical and Electrophysiological Biomarkers.
Gabriella Gobbi
Healthy ParticipantsPlacebo - ControlPsilocybin
Not Yet Recruiting·Phase 2·ketamine
Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder
University Hospital, Toulouse
Infusion of Ketamine in Severe Borderline Personality DisorderBorderline Personality Disorder (BPD)
Not Yet Recruiting·N/A·Other
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
Ente Ospedaliero Ospedali Galliera
FrailyAbdominal SurgeryPostoperative Cognitive Dysfunction (POCD)
Not Yet Recruiting·Phase 1·psilocybin
The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function
Manoj Doss
Healthy
Not Yet Recruiting·Phase 2·Other
Effect of Opioid-Sparing Anesthesia on Postoperative Opioid Consumption and Pain in Elderly Patients Undergoing Spine Surgery
Massachusetts General Hospital
Opoid ManagmentPain Management
Not Yet Recruiting·Phase 2·ketamine
Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse
University of Oklahoma
Head and Neck Cancer
Not Yet Recruiting·N/A·Other
Comparison Between Opioid-Free Anaesthesia Versus Opioid Based Anesthesia in Reduction Postoperative Nausea and Vomiting (PONV)After Thoracoscopic Lung Resection.
Sohag University
PONV
Not Yet Recruiting·N/A·ketamine
Ketamine Treatment for Treatment-Resistant Depression - the Role of Framing
Valdemar Landgren
Treatment Resistant Depression (TRD)
Not Yet Recruiting·Phase 2·ketamine
Behavioural Activation Therapy and Ketamine for Treatment-Resistant Depression
The Royal's Institute of Mental Health Research
Treatment Resistant DepressionMajor Depressive Disorder (MDD)
Not Yet Recruiting·Phase 1·psilocybin
Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study
University of Wisconsin, Madison
Well-Being, PsychologicalPsychedelic Experiences
Not Yet Recruiting·Phase 1·LSD
Shortened LSD Intervention for Major Depressive Disorder
Johns Hopkins University
Major Depression ModerateMajor Depression SevereMajor Depression
Not Yet Recruiting·Phase 1·psilocybin
The Effects of Psilocybin on Social Connectedness
Yale University
LonelinessGrief
Not Yet Recruiting·Phase 2·psilocybin
Assessing of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
University of New Mexico
PTSDPTSD - Post Traumatic Stress DisorderMajor Depression+1 more
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
Brigham and Women's Hospital
Alcohol Use Disorder
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin Microdosing on Cognition, Mood and Quality of Life
Yale University
Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI
Not Yet Recruiting·N/A·ketamine
Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.
China-Japan Friendship Hospital
Knee OsteoarthritisReplacement, KneeElective Surgical Patients+1 more
Not Yet Recruiting·Phase 4·ketamine
Intraperitoneal Ketamine Versus Fentanyl as Adjuvants to Bupivacaine in Laparoscopic Cholecystectomy
Assiut University
Postoperative Pain
Not Yet Recruiting·Phase 4·ketamine
Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis
University of Mississippi Medical Center
Vaso-Occlusive Pain Episode in Sickle Cell DiseaseSickle Cell Disease (SCD)
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder
Indiana University
Treatment Resistant DepressionSubstance Use Disorders
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)
NYU Langone Health
IBS - Irritable Bowel Syndrome
Not Yet Recruiting·N/A·ketamine
Intra-Sessional Autonomic Arc Detection in Ketamine-Assisted Therapy for PTSD: A Signal Characterisation Pilot Study
Adriaan Dirk van der Wart
Post-Traumatic Stress Disorder
Not Yet Recruiting·N/A·ketamine
Esketamine Versus Sufentanil for Sedation in Patients Undergoing ERCP
Ren Da
Biliary Tract DiseasesProcedural Sedation and Analgesia
Not Yet Recruiting·N/A·Other
Biomarker Discovery for Suicide Precision Circuit Therapeutics
Massachusetts General Hospital
Suicidal Thoughts and BehaviorsMajor Depressive Episode (MDE)
Not Yet Recruiting·Phase 2·psilocybin
Study of Psilocybin Under Anesthesia Controlled by EEG
Stanford University
Major Depression
Not Yet Recruiting·Phase 4·ketamine
Biomarker-Guided Antidepressant Selection
Weill Medical College of Cornell University
Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)rTMS+2 more
Not Yet Recruiting·Phase 2·ketamine
Pilot Randomized Control Trial Comparing Oral Ketamine and Oral Oxycodone for Pain Control in Emergency Department Patients
Albany Medical College
Pain Management
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy
Emory University
PTSD
Not Yet Recruiting·Phase 2·psilocybin
Group Retreat Psilocybin Therapy for Healthcare Clinicians With Loss of Meaning in Their Work and Symptoms of Depression
University of Washington
DepressionAnxiety
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy as a Treatment for Depression
Washington University School of Medicine
Depression
Not Yet Recruiting·Phase 2·ketamine
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
University of Rochester
Treatment Resistant Depression (TRD)Chronic Pain
Not Yet Recruiting·N/A·MDMA
Circulating Oxytocin Changes in Response to MDMA vs. Placebo in Adult Patients With Autism Spectrum Disorder and Matched Healthy Controls
University Hospital, Basel, Switzerland
Autism Spectrum Disorder
Not Yet Recruiting·N/A·Other
Multimodal Pharmacological Study of Clinical Cohorts for Major Depressive Disorder
Shanghai Mental Health Center
Major Depressive Disorder (MDD
Not Yet Recruiting·N/A·LSD
Effect of LSD on Renal Function in Cirrhosis Patients With Portal Hypertension Bleeding (2-Year Follow-Up)
Northern Jiangsu People's Hospital
Cirrhosis, LiverSplenectomy; StatusRenal Function Abnormal+1 more
Not Yet Recruiting·Phase 1·Other
Opioid-free Anesthesia and Postoperative Delirium
Qianfoshan Hospital
Postoperative DeliriumGastrointestinal Tumors
Not Yet Recruiting·Phase 2·psilocybin
Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy
Kyle Greenway
Treatment-Resistant Major Depressive Disorder
Not Yet Recruiting·N/A·ketamine
A 2×2 Factorial Randomized Controlled Trial for ERCP
Gang Chen
Biliary and Pancreatic DiseasesEndoscopic Retrograde Cholangiopancreatography (ERCP)
Not Yet Recruiting·N/A·ketamine
Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery
Tanta University
ObesityPostoperative PainBariatric Surgery
Browse by Condition
View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.